4945 resultaten
Consumption of foods containing L-arabinose will improve glycaemic and insulinemic response.
Type 2 diabetes is a major threat to human health. Disruption of the circadian timing system is associated with metabolic changes. Disturbance of the daily light and dark rhythm could contribute to this phenomenon and effects metabolic pathways. We…
The study will investigate the effect of a synbiotic test product compared to a control product on the composition and metabolic activity of the gut microbiota of C-section delivered infants.
We hypothesize that alfentanil will reduce maximum pain score by at least 1.3 point on a 11-point numeric rating scale.
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Acute challenges with cocaine and cannabis will induce two opposing dopaminergic states in the brain. Cocaine will stimulate dopamine release leading to hyperdopaminergia whereas cannabis will reduce central dopamine levels resulting in…
OTR4120 will improve healing of chronic ulcers.
The central hypothesis of our study is that routine postsurgical anesthesia visits reduces postoperative 30-day mortality by 30%.
Counteract the process of mental deterioration in elderly people through enhancement of their EPA-DHA status.
We hypothesize that our individual rehabilitation program will be (cost-)effective regarding the primary and secondary health- and work-related outcome measures of work in cancer survivors with an employment contract, compared to care as usual.…
The administration of probiotics to breastfeeding females exert a direct influence on the development of the infant gut microflora through the transference of selected strains.
Brain activity in people with schizophrenia differs when compared to brain activity of people who do not have this condition. There is evidence that the negative symptoms of schizophrenia are related to reduced cortical activation involving the…
Salmeterol has an inhibitory effect on both allergen and allergen/LPS induced inflammation in asthmatics while on maintenance treatment with low dose corticosteroids.
1-2 intramuscular injections with 100 mg dexamethason in persons without arthritis but with elevated serum levels of rheumatoid factor and or anti-CCP will lead to a reduction in antibody concentrations after 6 months and possibly to a lower…
This international, multi-centre, double blinded, placebo-controlled, randomised clinical trial will be performed: To assess the effectiveness of one year of alternate days Levamisole treatment in a dose of 2.5 mg/kg in the prevention of relapses…
To determine the safety and tolerability and to assess the PK and performance of VB5-845D-800CW in healthy volunteers and patients
1. Cannabis use increases striatal dopamine release 2. Striatal dopamine release predicts cannabis induced-psychotic experiences 3. Cannabis-induced striatal dopamine response varies as a function of genetic risk for psychosis
Dystonia associated with reflex sympathetic dystrophy responds markedly to intrathecal baclofen (ITB).
We postulate that faecal microbiota transplantation (FMT) from obese donors in patients with cancer can improve satiety (appetite) and subsequently nutritional status. Secondly, FMT might restore the gut barrier function and hence reduce systemic…
Assess the safety and tolerability of single ascending IV bolus doses of ABP-700