4945 resultaten
The peripheral chemoreceptors in the carotid bodies are sensitive to changes in the tensions of oxygen and carbon dioxide in the arterial blood and protect the body against hypoxia, hyper- and hypocapnia and acidosis/alkalosis. The ventilatory…
Objectives: 1. To investigate the added effects of eplerenone on top of ACEi, with and without dietary sodium restriction, on residual albuminuria, hypertension, and tubular injury markers, in patients with diabetic nephropathy; 2. To investigate…
Single dose intranasal dexmedetomidine can be administered safely to elderly people as premedication with respects to hemodynamic changes, irrespective of the concurrent use of betablocking medication
The hypothesis to be tested is that the outcome in arm B is better than in arm A.
Approximately 1/3 of persons with IGT develops type 2 diabetes mellitus in 5-10 years time. Acarbose is an alpha-glucosidase inhibitor decreasing post-prandial glucose levels, without the risk of hypoglycemia. The prevention of diabetes with…
This is a pharmcological study to examine the ability to reverse respiratory depression from opioids such as morphine and M6G by low dose naloxone.
The main objective of this study is to investigate to what extent the acute effects of MDMA on cognitive function, prolactin and cortisol levels, body temperature, heart rate and blood pressure are influenced by co-exposure to THC.
OTR4120 will improve healing of split-skin graft donor sites.
the active treatment group has an improvement of at least 10 points of DASH functional outcome more than the placebo group.
Adjuvant therapy of levamisole to prednisolone prevents relapses in children with a first episode of idiopathic nephrotic syndrome.
1. Patients with anxiety disorders show an increase of autonomy after the Autonomy-Group treatment; 2. Patients with anxiety disorders show a decrease of their symptoms after the Autonomy-Group treatment.
The protein-rich nutritional supplement increases muscle protein synthesis.
A. Rocuronium will induce impairment of carotid body function through blockade of cholinergic neurotransmission in carotid bodies resulting in a reduced or absent ventilatory response to isocapnic hypoxia. B. Sugammadex will completely restore…
Combined pneumococcal vaccination with influenza vaccinatoin reduces the occurrence of RTI in children with recurrent RTI.
A positive effect on mood is expected after LSD (20 µg) compared to placebo. The effect of LSD on mood is expected to differ depending on time of drug administration (morning vs evening).
Improving functional outcomes in rectal cancer surgery by a pelvic floor rehabilitation program.
To determine whether 4-FA can be safely administered in healthy volunteers in doses up to 150 mg
The overall hypothesis is that balance-specific exercise training only improves postural control of sway measured in standing and causes retention of the improved sway behavior and that such behavioral improvements correlate with changes in measures…
To induce tolerance for gluten in genetically predisposed children for coeliac disease through the introduction of small quantities of gluten during the period of breast-feeding.
Let µT denote the mean value of the composite IBS-SSS score under treatment with the active / GOS and µP denote the mean value of the composite IBS-SSS score under placebo, then the primary two-sided hypothesis to be tested is: • H0: µT - µP = 0 (i.…