4941 resultaten
Intervention with the food under study has a positive effect on cognitive performance in patients with mild to moderate Alzheimer's Disease.
Primary Objective: Aim of the study is to investigate whether sulodexide treatment reverses damage of the systemic glycocalyx in patients with DM type II. The effect of sulodexide will be addressed in this prospective cross-over study measuring…
To evaluate whether nitrofurantoin treatment for women with asymptomatic bacteriuria is effective in reducing the risk of preterm delivery and/or pyelonephritis (primary outcome) and bad neonatal outcome (secondary outcome). In addition, assessing…
Proof of concept: to study the effect of tianeptine on opioid-induced respiratory depression in healthy volunteers.
Is the application of CryoSeal (CS) by primary total knee replacement surgery beneficial for the patient with respect to a faster track and improved early (2 and 6 weeks) postoperative rehabilitation as determined by improved knee extension.
Prucalopride accelerates gastric emptying and increases esophageal contraction amplitude and LES pressure and subsequently reduces gastroesophageal reflux.
Premature infants born under 32 weeks tolerate bolus feeding better than semi-continuous nasogastric milk feeding, so that the number of days to reach full enteral feeding are less.
Imiquimod stimulates dendritic cell antigen presentation and migration to lymphnodes. Since dendritic cells are present in the dermis and epidermis, vaccination in the dermis could target these cells and, with simultaneous topical imiquimod…
In view of the poor prognosis of SSc, the presumed autoimmune origin, and the lack of available therapies, this disease is considered suitable for initial investigation of the tolerability and efficacy of anti B-cell therapy. In literature, there…
Het effect onderzoeken van acute verhoging van groeihormoon waardes op cognitief functioneren in gezonde mensen, en uitvinden of de relatie tussen groeihormoon en cognitie direct of indirect is. Doel van het onderzoek: We willen de acute effecten…
Hypotheses: 1. That there will be a change in the negative sense in sensory stimulus processing after 2 weeks and possibly up to 3 months after anaesthesia as measured with I/T SP; 2. That there is a relation between postoperative changes as…
We will investigate the relationship between S(+)-ketamine plasmaconcentrations and its analgesic effect to estimates the onset/offset times of ketamine and potency parameters for various analgesia tests. This will allow the safer administration of…
PK and PD effects of JNJ-61393215
The metabolic syndrome and its visceral adiposity may well be beneficially influenced by PPAR-ã agonist, by redistributing fat mass from central to peripheral stores and improving insulin resistance. The inflammatory atherosclerotic response, as…
Regularly scheduled administration of paracetamol, compared to placebo, leads to better quality of life, daily functioning, mood, and less pain, care dependency, behavioural problems and psychotrophic medication use.
The hypothesis is that magnesium oxide is effective in reducing the intrafraction motion of the prostate during radiotherapy treatment for prostate cancer.
Postprandial hyperglycemia has a negative effect on aortic elasticity in patients with impaired fasting glucose versus matched controls.
The treatment of Myofascial Trigger Points (MTrPs) in the trapezius muscle with ischaemic compression and ultrasound originated a short-term improvement of cervical mobility, relaxation of trapezius, and reduction of its sensitivity.
Fluoride rinse helps prevent caries more than optimal tooth cleaning alone.