716 resultaten
- The incidence of PONV will be higher in the group receiving dexamethasone alone - There will be no significant difference in the incidence of PONV between the two groups receiving two anti-emetic drugs - There will be less postoperative agitation…
Inhibition of the H1 receptor will lead to an improvement of rectal sensitivity, followed by less abdominal symptoms in patients with irritable bowel syndrome.
Computerized decision support (CDSS) for tailoring prevention to the local circumstances using the guidelines of the Dutch college of general practitioners has impact on preventive activities in the primary care setting
In EPF, the sequential combination of mifepristone with misoprostol is superior to the use of misoprostol alone in terms of complete evacuation of products of conception, patient satisfaction, complications, side effects and costs.
To assess the impact of the physical form of five different cocoa matrices on the bioavailability of the monomeric flavan-3-ols.
Treatment with Botox will give a better healing rate for anal fissures compared to treatment with isosorbidedinitrate ointment.
We hypothesize that helium postconditioning reduces ischemia reperfusion injury following an acute myocardial infarction and thereby reduces the size of infarction. Secondly, we hypothesize that this reduction leads to improved myocardial function,…
Microalbuminuria in diabetes mellitus is not only associated with progression to renal disease, it is also a potent predictor of cardiovascular disease and thus may reflect widespread vascular damage. Endothelial dysfunction is one of the first…
The primary aim is to determine if there is a difference between tibolone and placebo or if there is a difference between raloxifene and placebo. The secondary aim is to determine if there is a difference between tibolone and raloxifene. Primary…
Part 1: To determine the respiratory response of low and high doses of GAL-021 in conjunction with a low dose of opioids and hypercapnia in healthy subjects. Part 2: To determine the respiratory response of low and high doses of GAL-021 in…
rTMS has a positive effect in the treatment of depression.
Long-chain triglyceride (LCT) emulsions with di-unsaturated fatty acids will lead to enhanced postprandial satiety and reduced energy intake in a subsequent meal, as compared to LCT emulsions with mono-unsaturated or saturated fatty acids.
Compliance with patching therapy for amblyopia can be improved by an educational programme aimed primarily at the child.
• To evaluate the safety and tolerability of three oral dose levels of LTI-291 following 28 days of LTI-291 treatment in patients with Parkinson’s Disease with GBA-PD. • To characterize the plasma and CSF pharmacokinetics (PK) of LTI-291 following…
Hypotheses: 1. That there will be a change in the negative sense in sensory stimulus processing after 2 weeks and possibly up to 3 months after anaesthesia as measured with I/T SP; 2. That there is a relation between postoperative changes as…
We will investigate the relationship between S(+)-ketamine plasmaconcentrations and its analgesic effect to estimates the onset/offset times of ketamine and potency parameters for various analgesia tests. This will allow the safer administration of…
Depressive symptoms are common in older persons, often associated with poor physical function and vitamin D deficiency (serum 25-hydroxyvitamin D < 50 nmol/l). Simple and cheap interventions to prevent depression are lacking. Vitamin D…
Intranasal insulin will improve development and behaviour in children with Phelan-McDermid syndrome.
We hypothesize that restoration of gut microbiota diversity (by using donor FMT enriched in Desulfovibrio strains) could have explicit beneficial effects on glucose metabolism and NAFLD (via improved fructose catabolism), which is driven by…
Het effect onderzoeken van acute verhoging van groeihormoon waardes op cognitief functioneren in gezonde mensen, en uitvinden of de relatie tussen groeihormoon en cognitie direct of indirect is. Doel van het onderzoek: We willen de acute effecten…