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We hypothesize that PHA-022121 will be more effective in both the treatment and prophylaxis of acute angioedema attacks in patients with acquired C1-inhibitor deficiency when compared to placebo.
-Six weeks of treatment with a supplementary low dose of clonidine to the current medical treatment of clozapine resistant patients will effectively reduce symptom severity and cognitive impairments in therapy resistant schizophrenia patients -…
Reduced dermal blood flow response to capsaicin application and saline iontophoresis after propranolol ocompared to placebo administration.
1: Long term use of fluoxetine causes the excitability of the primary motor area of the brain to change 2: Long term administration of fluoxetine causes the muscle activation patterns to change
In adult congenital heart disease patients with exercise-induced pulmonary arterial hypertension, treatment with bosentan lowers the mean pulmonary arterial pressure, which may result in improvement of the cardiopulmonary circulation,…
Vitamin D supplementation reduces the incidence of delayed union in fracture patients with a vitamin D insufficiency, compared to placebo.
Ghrelin administration in comatose patients after cardiac arrest is safe, causes no serious adverse events relatable to ghrelin use and it improves functional recovery in these patients.
Crohn’s disease (CD) is a chronic inflammatory bowel disorder (IBD) with a major impact on quality of life. Mucosal healing is an important treatment outcome to prevent long term complications of the disease. Regulatory M2 type macrophages play a…
1. Participants in the CBM training condition have weaker smoking related cognitive biases than those in the placebo condition 2. Improvement in smoking cessation outcomes in participants in the CBM training condition compared to those in the…
1.We expect participants in the experimental condition to show a reduced gmbling behaviour 2. We expect participants in the experimental condition to show a decrease in approach bias towards gambling cues, and weaker approach implicit associations…
An intervention with Methylphenidate, Melatonin or Light Therapy will lead to changes in visual functioning.
AN-PEP helps to digest gluten in vivo.
Pelvic floor muscle spasms resulting in chronic pelvic pain may occur as a primary event or secondary to a physical, psychological or pathological factor. First-line treatment consists of pelvic floor physiotherapy. When first-line treatment fails,…
The main objective is to evaluate the efficacy and safety of phenytoin cream in patients with neuropathic pain due to CIAP
rhDNase improves lung function in children with persistent asthma who have persistent obstructive pulmonary function; Treatment of mucus impaction is an interesting alternative approach to treat peripheral airflow limitation in asthmatic patients.…
It is expected that acute challenges with cocaine will induce two opposing effect on creativity. That is, cocaine will increase mood leading to enhancement in divergent but not in convergent thinking.
Intravenously administred ascorbic acid improves reduction in wound area of a vascular surgical wound of at least 30% within 4 weeks post-surgery.
-Low dose radiotherapy has positive effects on pain and functioning in osteoarthritis of the hand and knee -Low dose radiotherapy is effective on reducing inflammatory signs of osteoarthritis of the hand and knee
Hypothesis 1: Participants in both conditions (experimental and placebo) will show a reduction in gamble problem severity immediately post-intervention and at 3-and 6-month follow-ups. However, participants in the experimental condition will show a…
1. The use of food supplements containing vitamin C with quercetin and other flavonoids can reduce inflammation clinically (assessed by means of periodontal parameters), and systemically (assessed by means of biomarkers), in patients diagnosed with…