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A study to evaluate the different levels of attention and valence direction for erotic stimuli, in relation to genital and subjective sexual arousal in healthy female subjects and healthy female subjects with Female Sexual Dysfunction.

In the present placebo controlled study we will investigate the influence of valence on attention when viewing visual erotic stimuli. Especially when under the treatment condition of testosterone with sildenafil. In addition, we will investigate the…

Dexamethasone for Cardiac Surgery study

A single, prophylactic dose of dexamethasone during cardiac surgery reduces the incidence of major postoperative complications.

Effect on bone turnover and BMD of low dose oral silicon as an adjunct to calcium/vitamin D3 in a randomized, placebo-controlled trial.

To investigate the effect of low dose oral silicon as an adjunct to calcium/vitamin D3 on markers of bone turnover and BMD.

A randomized, double blind, placebo-controlled trial to evaluate the clinical efficacy and the structure modifying properties of etanercept 50/25 mg sc weekly in patients with erosive OA of the interphalangeal finger joints.

Etanercept is able to improve clinical and functional abnormalities and to halt or reverse radiographic changes in inflammatory erosive hand osteoarthritis by virtue of blocking a major pro-inflammatory cytokine, tumor necrosis factor (TNF).

Elective laparoscopic appendectomy for chronic right lower abdominal pain;
outcome of a prospective randomised
double-blind controlled surgical trial.

Elective laparoscopic appendectomy is a usefull procedure in patients with chronic or recurrent right lower abdominal pain.

The effect of specialized nutritional intervention with a disease-specific sip feed (Cubitan) in the support of patients with pressure ulcers.

Improving the rate stage III/IV pressure ulcers heal through nutritional support.

The effect of glycopyrroniumbromide on hypersalivation in patients with Parkinson's disease: a randomised, cross-over, doubleblind, placebocontrolled trial.

The aim of this study is to prove the efficacy of 3 times daily 1 mg glycopyrronium bromide admixture versus placebo admixture in patients with PD with hypersalivation. Furthermore, the safety of glycopyrronium bromide used in the mentioned dosage…

Misoprostol in the management of retained placenta, a safe alternative for manual removal? A randomised controlled trial.

The use of 800 mcg of misoprostol prevents manual removal of the retained placenta in 80% of cases.

The effects of SCH351125 on posriatic plaque immunohistochemistry, and chemokine expression in patients with moderate to severe psoriasis (protocol No.P03657) SCH351125.

Several reports have indicated that the chemokine receptor CCR5 and its ligands, escpecially CCL5 (formerly known as RANTES), may play a role in the pathogenesis of psoriasis. CCR5 targeted treatment could therefore be a therapeutic option for…

Homebased Medication Review

An homebased medication review intervention conducted by a community pharmacists in close collaboration with the GP and patient improves the quality of pharmacotherapy in elderly patients.

Low field TMS as pain treatment as measured with quantitative sensory testing.

Low field TMS can reduce nociceptive and neuropathic pain.

A double blind placebo controlled study on the effect of cerivastatin on the process of atherosclerosis in non-insulin dependent diabetes mellitus (type 2).

To assess the effect of statin therapy on the process of atherosclerosis in type 2 diabetes without manifest cardiovascular disease.

A Randomised, Double-blind, Controlled Study on the Effect of One Year Administration of a Nutritional Concept on Immunological Status in HIV-1 Positive Adults not on Antiretroviral Therapy

Improving the immunological status of HIV-1 infected adults not on antiretroviral therapy through nutritional support.

Coffee consumption and glucose tolerance in humans.

Intake of chlorogenic acid and trigonelline reduce postprandial glucose concentrations during an oral glucose tolerance test relative to placebo.

Vermindert duloxetine de neuropathische pijn bij patiënten met het centrale pijnsyndroom?
Een dubbelblind gerandomiseerd onderzoek.

We tested, in a randomized, double-blind, placebo-controlled trial, the effects of duloxetine on pain relief, tolerability, health status, and quality of life in patients with central neuropathic pain.

Probiotics in the prevention of traveller's diarrhoea.

A relative reduction of 50% in the occurence of traveller's diarrhoea.

Adenosine Administration during and after Primary percutaneous coronary intervention in acute myocardial infarction – a Randomized Controlled Trial (ADAPT).

Intracoronary adenosine injections will lead to a significant reduction in the amount of residual ST-segment deviation.

The effect of intermittent bolus nasogastric milk feeding versus semi-continuous milk feeding in preterm infants on TOLerance.

Premature infants born under 32 weeks tolerate bolus feeding better than semi-continuous nasogastric milk feeding, so that the number of days to reach full enteral feeding are less.

Intradermal Hepatitis-B-vaccination in non-responders after application of imiquimod 5% at the site of vaccination.

Imiquimod stimulates dendritic cell antigen presentation and migration to lymphnodes. Since dendritic cells are present in the dermis and epidermis, vaccination in the dermis could target these cells and, with simultaneous topical imiquimod…

Diabetes intervention study in Hindustani Surinamese

A systematic screening and a lifestyle-intervention for pre-diabetes targeted at the Hindustani Surinamese population will prevent or postpone the onset of diabetes mellitus type 2.