54 resultaten
A home-based peripheral muscle training program (Five Basic Exercises program (5BX)) is more effective in [a] increasing exercise capacity (e.g. peak work rate) and [b] patients’ preferred occupational performance when it is preconditioned by…
It is hypothesized that aerobic exercise therapy (AET) and cognitive behavioural therapy (CBT) are both effective in improving activities and QoL in patients with Amyotrophic Lateral Sclerosis (ALS) compared to the usual care.
This study is therefore aimed at quantifying the relative contribution of the two major receptor systhems involved in S(+) ketamine and methadone induced analgesia and side effects( respiratory depression,sedation,miosis).
This study will test the hypothesis that Sevoflurane attenuates oxidative damage, complement, enothelial, thrombocyt and neutrophil activation and inflammation to human ischemia reperfusion injury of the myocardium.
Progesterone treatment for women with a short cervical length is effective in reducing the risk of preterm delivery.
We hypothesize that subjects (Asian or Caucasian) with the COMTH allele (Val/Val polymorphism) respond stronger to the GT treatment than subjects with the COMTL allele (Met/Met polymorphism), consequently have an increased EE and that the genetic…
It is hypothesized that in the population of frequent cannabis users, cross tolerance will have developed for the effects of alcohol, and that therefore the behavioral effects after alcohol will be less when given in combination with cannabis.
Activation of SIRT1 (silent information regulator transcript) results in inhibition of inflammation in humans.
To compare the differences in duration of delirium in delirious patients receiving anti-psychotic therapy + melatonin or anti-psychotic therapy + placebo.
Development of early-onset dementia (EOD) is very radical and disabling for both patient and family, due to the still prominent role of the patient in society. Except for knowledge on cognitive disorders not much is known about other disabling…
In line with results from recent pharmacological studies, it is expected that: 1. Inhibiting the cholinergic system by Inversine (Mecamylamine Hydrochloride) results in an impairment of disengagement, but will not affect bias; 2. Inhibiting the…
Colesevelam is a bile sequestrant that not only improves lipid parameters, but also improves glycemic control. The workingsmechanismen of colesevelam is yet unknown. We hypothezize that treatment of obese insulin resistant subjects with colesevelam…
Adalimumab is a more effecient drug than oral claritromycin alone in the treatment of hidradenitis suppurativa.
Vitamin K2 can increase the carboxylation of the Matrix-Gla-Protein.
Augmentation of the contralateral hip in patients with a low energy hip fracture over 50Y willdecrease the change of a new hip fracture on the augemented side.
Non-invasive ventilation reduces the inflammatory response to exercise.
We hypothesize that administration of intranasal insulin: 1. Inhibits endogenous glucose production, indepently of systemic insulin; 2. Increases the insulin concentration in the cerebrospinal fluid (CSF).
High free fatty acids lower central serotonergic responsivity.
The aim of this study is to develop and evaluate a patient-oriented treatment decision aid (PTDA) focussing on shared goal-setting and decision making, which is tailored to the needs and capacities of a heterogeneous group of patients with type 2…