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1) Implementing TIPP will prevent acute emergency room (ER) visits, rehospitalisations and inappropriate referrals 2) Implementing TIPP improves transitional patient safety culture 3) Although TIPP aims at reducing transitional incidents,…
The aim of this study is to investigate wether a eccentric exercise program is more effective in patients with primary subacromial impingement compared to a conventional exercise program. Several studies about the effect of eccentric training in…
• CT based Signature™ will result in a comparable percentage of prosthesis that is placed correctly (within guidelines of 3 degrees varus and 3 degrees valgus). • CT-based Signature™ will result in a comparable alignment of the prosthesis as…
1) Tapering of SSRIs with added preventive cognitive therapy (CT) increases the risk of clinically relevant maternal relapse of depression in excess of [absolute] 15% compared to continuation of SSRIs. If rejected, then discontinuation is deemed non…
To elongate the service life of the implantable neurostimulator while achieving a minimal improvement of 50% of the symptoms of overactive bladder compared to baseline.
We expect paediatric pelvic physiotherapy in addition to conventional treatment to be more (cost)- effective than conventional treatment alone, after 8 months follow-up.
Minimal invasive fusion results in a longer time spent in satisfactory symptom state (based on the ODI being below 20) than open fusion of the lumbar spine in patients with one- or two-level spinal stenosis and instability, associated with…
More patients in primary care will be treated according to (evidence based) guidelines if general practices receive feedback on a patient specific level then if they receive feedback on practice level comparing recipients practice with median…
This study will use a Randomized Controlled Trial (RCT) to evaluate the effectiveness and underlying mechanisms of the video game Mindlight, a newly developed anxiety-reducing training for children. Mindlight and a control game will be played for…
Blended eHealth treatment is evenly effective and more cost-effective than treatment as usual.
We hypothesize that endoscopic ultrasound-guided celiac ganglia neurolysis (EUS-CGN) is more effective in achieving adequate pain reduction in malignant upper-abdominal pain or back pain than percutaneous splanchnic nerve neurolysis (P-SNN)
Intraoperative fluorescence tracing of the sentinel node using the opto-nuclear probe is feasible.
Hysteroscopic morcellation of placental remnants has a lower risk of postoperative intrauterine adhesion formation compared to ultrasound guided electric vacuum aspiration.
Brown adipose tissue (BAT) is thought to be involved in human glucose and lipid metabolism, however the mechanisms by which this adipose tissue is activated remain to be elucidated. Recent data in db/db mice have suggested that oral butyrate has…
Analysis of the lymphatic drainage pattern using 99mTc-Senti-Scint identifies the same SNs, but fewer higher-echelon nodes, as when ICG-99mTc-nanocolloid is used.
Primary objective: To determine the safety of once daily inhalation of the recommended daily dose of tobramycin with the Akita® and the PARI-LC® Plus nebulizer in patients with CF. Systemic absorption can be used as surrogate parameter for safety.…
The individual counselling intervention will significantly
Increasing medication adherence in rheumatoid arthritis (RA) might reduce disease activity and the need to prescribe more expensive (biological) anti-rheumatic drugs. The usage of drug monitoring devices (like Medication Event Monitoring System (…
Monotherapy with aspirin or oral anticoagulation after TAVI is safer than the addition of clopidogrel for 3 months, without being less clinically beneficial.
This study focuses on PTSD due to repeated and prolonged interpersonal abuse in childhood (eg sexual and / or physical abuse) within the immediate environment. By using a Randomized controlled design, we examine whether Imaginary Exposure is more…