106 resultaten
Trifluridine is primarily metabolized through degradation by thymidine phosphorylase to the inactive metabolite 5-(trifluoromethyl)-uracil (FTY) without any involvement of the cytochrome P450 enzyme system. The primary route of excretion of…
Main question: Is Theraplay an effective treatment method for children with ASD and what is the effect of treatment with Theraplay on their parents? Prior RCTs proved that Theraplay leads, among other things, to a decrease in internalizing problem…
Awake craniotomy improves safety and efficacy during surgery for glioblastoma in eloquent areas
Individual-directed resilience training can reduce chronic stress and prevent burnout among students
Reducing the dose in the setting of therapeutic drug monitoring (TDM) does not affect clinical disease activity and safety, while it will reduce costs.
LEND surgery is a (cost)-effective treatment option for patients with Diabetes and lower extremity compression neuropathy, compared to conventional (non-surgical) care.
Paravertebral analgesia is associated with superior quality of recovery by achieving comparable pain control whilst having less side-effects.
The pharmacokinetics of erlotinib 150mg QD is comparable to the pharmacokinetics erlotinib 75mg + ritonavir 200mg QD.
Our hypothesis is that we can achieve comparable clinical outcomes with accurate virtual 3D planning and surgical preparation only.
Our hypothesis is that; 1) the information video contributes to an improved understanding of the lumbar puncture procedure, and 2) reduces anxiety for the procedure.
Non-inferiority of tsDAMRD first versus TNFi first in terms of ACR50 response at 12 weeks
Based on most recent insights in AAV treatment, the present study intends to evaluate whether combining rituximab with cyclophosphamide is superior to current standard of care with rituximab only to induce a favorable immunological state of MRA in…
- Personalized psychological care is more efficacious than standard, non-personalized psychological treatment in improving functioning of cancer survivors. - Personalized psychological treatment is more efficacious than standard, non-personalized…
The effect on compliance with rehabilitation therapy after trapeziectomy, in patients assessing their possible selves before starting rehabilitation therapy, by evaluating PROMS and compliance. Hypothesis: that patients assessing their possible…
The present study will assess the composition of the oral microbiome in patients who have been referred to the NKCV (Nederlands Kenniscentrum Chronische Vermoeidheid) for treatment for complaints of severe and protracted fatigue. Objective…
EBUS/EUS-B sampling of mediastinal/hilar lymph nodes and/or primary lung tumors with the Acquireᵗᵐ 22G TBNB needle has a higher suitability rate for the assessment of PD-L1 expression in comparison to the regular 22G TBNA needle in patients with…
Thyroid hormone withdrawal leads to permanent DNA modifications that are not seen in patients treated with rhTSH.
Training therapist in optimized ROM (Feedback Informed Treatment) and Shared Decision Making will result in less drop-outs, better outcomes, better patient experience and more favourable attitude ot therapist towards Routine Outcome Monitoring
The YEARS algorithm is non-inferior to management by CTPA with regard to 3-month recurrent VTE rates and will reduce the rate of unnecessary CTPA in patients with clinically suspected PE and active malignancy.
Compared to plate fixation, intramedullary fixation allows a minimally invasive technique using smaller incisions and a low-profile implant, causing less postoperative complications by avoiding extensive soft tissue injury, eventually resulting in a…