3601 resultaten
Our hypothesis is that high-dose, pulsatile sorafenib may exhibit improved efficacy with an acceptable toxicity profile compared to standard continuous dosing. AUC escalation cohorts are used instead of the conventional dose escalation cohorts,…
The aim of this study is to validate the Dutch versions of the PainDETECT questionnaire PD-Q and the ‘Douleur neuropathique en 4 questions’ (DN4) for use in primary and specialist medical care settings for patients with LBP and NSP and patients with…
Implementation of Module CH leads to better tailored care, improved functioning of the user and more efficient use of absorbent incontinence aids.
urge incontinence is caused by overactivity of the detrusor muscle of the urinary bladder. Electrical stimulation of the pelvic floor muscles can suppress detrusor overactivity. The miniaturo tm-i system is designed to deliver mild electrical…
The primary hypothesis is that the effect of tubal flushing with oil-based contrast results in higher ongoing pregnancy rates compared to water-based contrast medium.
Exploration of the effects of AAT in adults with an Autism Spectrum Disorder (because this study has an explorative character, there is no hypothesis formulated)
Peroperative fluorescent imaging of the bile ducts will improve visibility and results in early identification of the common bile duct and the cystic duct during laparoscopic cholecystectomy in patients at risk for bile duct injury.
VIM-positive Pseudomonas aeruginosa can be found in other body sites besides throat and rectum, which are currently used as the standard surveillance culture sites.
We expect the SPOT-25 to correlate with all three measurement instruments. We expect correlation between the change score in the “hearing function” domain of the translated SPOT-25 and the Glasgow Benefit Inventory to be higher than correlation…
Bariatric surgery leads to vitamin deficiencies and a malabsorptive state that impairs embryonic growth.
Does MS grey matter pathology progress faster in regions with more damage in connected white matter?
Our hypothesis is that MS grey matter pathology, and thereby disease burden and clinical outcome, can be better predicted by looking at damage in the connected white matter in early RRMS patients
The depression prevention program ("Op Volle Kracht") will be delivered by teachers in the school curriculum in schools with adolescents from high-risk background. It is expected that adolescents who receive the interventions will show…
Cerebral amyloid angiopathy is an important predictor for cognitive decline after intracerebral hemorrhage
Similar or better fixation, migration and functional outcomes compared to other existing techniques
Is it possible with the course of cytokines in the first two days of life to start antibiotics selectively in infants suspected for an EOS (early onset sepsis) and to stop prescribing antibiotics in infants who already receive antibiotics
MIA is a good alternative for the CA, with comparable diagnostic performance. It will lead to an increase in clinical autopsy rates, which have significantly decreased over the last decades in both academic and non-academic medical centers.
We hypothesise that the health behaviour of pregnant women is influenced by the measures to prevent the spread of COVID-19. It is not clear however, if it is positively affected (because of having more time, providing online options, creating a…
We hypothesize that increased disease activity (i.e. more inflammation) is associated with an increased risk of developing ID.
The goal of this intervention is: 1. To improve the support for successful social participation for adolescents with a visual impairment 2. To develop Mentor Support for the improvement of social participation in adolescents with visual impairments…
To determine the feasibility of the measurement protocol of a large prospective longitudinal study to describe the exercise capacity and physical functioning of critical illness survivors up to 5 years after discharge from the ICU.