50 resultaten
Increased physical exercise of patients with a prostate carcinoma has a positive effect on quality of life.
1. The use of food supplements containing vitamin C with quercetin and other flavonoids can reduce inflammation clinically (assessed by means of periodontal parameters), and systemically (assessed by means of biomarkers), in patients diagnosed with…
By making a child-profile (360°CHILDoc) online available for parents and youth, they will be more satisfied about the health service Accessibility of the Preventive Child and Youth Health Care (CYHC) and the integral CYHC- information about child…
Infant formulae with higher levels of milk fat result in improved fatty acids absorption as compared to standard formula.
In EPF, the sequential combination of mifepristone with misoprostol is superior to the use of misoprostol alone in terms of complete evacuation of products of conception, patient satisfaction, complications, side effects and costs.
We hypothesize that steering DBS will lead to a greater reduction of PD motor symptoms than ring-mode DBS. We will also separately measure the effect of the two types of DBS in people who have good response to ring-mode and those who don’t.
Primary Objective: Investigate the effect of modafinil (200 mg) and caffeine (300 mg) on vigilance in low, medium and high caffeine consumers during the circadian trough in order to determine: - To what extend vigilance during the circadian trough…
Faecal transplantation from a healthy donor can restore the dysbiosis present in adolescents with refractory IBS, thereby inducing improvement of the IBS complaints.
A. Rocuronium will induce impairment of carotid body function through blockade of cholinergic neurotransmission in carotid bodies resulting in a reduced or absent ventilatory response to isocapnic hypoxia. B. Sugammadex will completely restore…
The study will assess drug-induced change in performance in divergent thinking and goal-directed behaviour when comparing psilocybin to placebo, before and after an induction of stress. Additional study parameters include frontal-subcortical…
Metformin and hydrochlorothiazide attenuate polyuria in patients treated with tolvaptan
Doxepin hydrochloride 5% cream significantly reduces pruritus in burn patients in comparison with a placebo cream
Patients with ALS are routinely prescribed riluzole, the only registered drug for the treatment of ALS. This study will evaluate the concentration-effect relationship of riluzole (100 mg) and retigabine (300 mg) on axonal excitability measures. In…
If COMET increases the saliency of positive autobiographical memories, then memories that are activated during COMET (relative to no intervention control) should show an increase over time on all primary outcome measures, irrespective of medication…
We hypothesise that in the Subacromial Pain Syndrome (SAPS), a differentiation between primary peripheral (i.e. (peri)articular) and secondary pain due to altered processing of pain, i.e. central pain sensitisation, is needed. We further hypothesise…
The primary aim of the current research project is to establish whether the current Dutch vision screening in children aged 3-6 years old in PYHC can be improved by using plusoptiX, with regard to costs and screening performance.
We hypothesize that dietary nitrate supplementation improves muscle strength and muscle endurance performance.
The primary objective of the study is to examine whether the WhiteTeeth app used by orthodontic patients aged 12 to 16 improves oral health behavior and oral hygiene. Primary outcomes of this RCT are dental plaque levels, gingival bleeding upon…
The preventive HA formula will show on average a 40% risk-reduction for AD (54% when AD is not present in family history and 22% when AD is present in the family history) as compared to a standard formula. 2) The preventive HA will show a 30% risk…