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The main objectives of this study are: • To gain insight into the effectiveness of the Healthy Working Approach on need for recovery in elderly care workers over one year. • To gain insight into the process of implementing the Healthy Working…
The main clinical challenge remains to identify patients who may benefit from aggressive local treatment (stereotactic radiotherapy, SBRT) of soft tissue oligometastases: for which patients can systemic treatment be postponed? Patients who are…
The study aims to assess the efficacy (in terms of growth response over the years of treatment, including final height) and safety of a treatment regimen consisting of: 1. Authentic biosynthetic growth hormone (GH) in a dosage of 4 IU/m2/day between…
Interhospital transport of IC-patients can be escorted solely by an registered IC-nurse.
(1) Written imaginal exposure results in beneficial effects compared to no-intervention (2) Beneficial effects are greater for written imaginal exposure in the past tense than for written imaginal exposure in the present tense
Our first hypothesis is that both guided and unguided online CBT lead to a decrease in the severity of PCBD, PTSD, and depression symptoms. Our second hypothesis is that people allocated to the guided online CBT group will show a stronger decrease…
The tested intervention (level 5 intervention of Triple P, an intensive individual training for the family of children with behavioural problems) will cause a decrease in behavioural problems in children, dysfunctional parenting styles in parents,…
We hypothesize that lower renal region or cerebral NIRS values are correlated with a higher incidence of postoperative AKI in this study population
Maintenance thalidomide delays the time to progression with 50% in patients who do not progress after > 3 cycles of pemetrexed containing chemotherapy.
Cultured mesenchymal stem cells differentiated into osteoblasts and seeded on scaffolds can induce bone formation.
We hypothesise that there will be no (substantial) differences between both scans for all relevant parameters (e.g. fat mass, lean mass, and bone mineral density) when the same subjects are measured on the same day, under the same conditions.
The aim of this study is to determine a high level of agreement between readings obtained from the plasma levels and the Roche Accu-Chek Inform II.
urge incontinence is caused by overactivity of the detrusor muscle of the urinary bladder. Electrical stimulation of the pelvic floor muscles can suppress detrusor overactivity. The miniaturo tm-i system is designed to deliver mild electrical…
Are CBT and IPT following initial treatment effective interventions that prevent relapse of recurrence of depression in the long-term? What are the mechanisms of change in CBT and IPT?
VIM-positive Pseudomonas aeruginosa can be found in other body sites besides throat and rectum, which are currently used as the standard surveillance culture sites.
Cerebral amyloid angiopathy is an important predictor for cognitive decline after intracerebral hemorrhage
We hypothesize that therapeutic drug monitoring of risperidone in children with an autism spectrum disorder and comorbid behavioral problems will reduce metabolic side effect burden, while retaining clinical effectiveness.
We hypothesise that exercise may reduce risk of breast cancer, either directly or indirectly through a reduction in abdominal fat mass, by favouring the sex hormone profile and decreased insulin. Because the association between breast cancer and…
The hypothesis of the TRANSFORM II study is the non-inferiority of Sirolimus Coated Balloon versus Everolimus Eluting Stent in terms of Target Lesion Failure
We hypothesize that clinicians exposed to this intervention are more likely to adopt SDM behaviors than clinicians who do not. A secondary aim is to evaluate whether patients perceive more involvement in the decision-making process.