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We hypothesise that exercise may reduce risk of breast cancer, either directly or indirectly through a reduction in abdominal fat mass, by favouring the sex hormone profile and decreased insulin. Because the association between breast cancer and…
Cross-transmission of antibiotic-resistant pathogens can be prevented by using closed suction systems (CSS) instead of open suction systems (OSS) in mechanically ventilated ICU patients.
Dietary intervention using the food for special medical purposes in question to address specific nutrient deficiencies has a positive effect on cognitive performance in patients with early Alzheimer’s Disease.
We hypothesized that forming implementation intentions may increase levels of physical activity.
Because little is known on the effective and safe dosage of propofol when used for control of intracranial pressure in head-injured patients, propofol blood and cerebrospinal fluid concentrations and pharmacodynamics are characterized in order to…
1. The level of suicide ideation is correlated with al ow level of positive future expectencies 2. Our future oriented training will help people to predict a more positive future 3. And this will lead to less suicide ideation
Improvement of the intestinal microflora of children consuming a fibre-enriched versus a standard paediatric tube feed.
The time constant of oxygen uptake during recovery of submaximal exercise is a reliable parameter to measure effects of exercise training in patients with chronic heart failure.
1. The intervention group will have a lower BMI/waist circumference, compared to the control group at follow-up; 2. The intervention group will have more favourable outcomes on the targeted behaviours, compared to the control group at follow-up; 3.…
1. Imipramine and Venlafaxine are comparable in efficacy in inpatients with a major depression; 2. Imipramine and Venlafaxine are comparable in tolerability; 3. Patients with a Venlafaxine plasma level < 195 µg/L show comparable…
FESS is effective: giving significant reduction of symptoms. The indication for FESS must be based on the symptoms of the patient and its duration, CT scan abnormalities and/or nasal endoscopic abnormalities, and a history of adequate conservative…
Usage of disease specific tube feed will improve glucose control in diabetic patients.
Type 2 diabetes is cause by progressive beta-cell dysfunction against a background of obesity and insulin resistance in susceptible individuals. Peroxisome proliferator-activated receptor (PPAR) gamma-mediated mechanisms are involved in the…
It is hypothised that a pain consult at the specialized pain clinic in combination with Patient Education Program is more effective in reducing average pain intensity compared to a pain consult alone. A pain consult at the specialized pain clinic is…
Systematic screening for type 2 diabetes in high-risk obese subjects, identified from the general population, can significantly reduce the diabetes-related cardiovascular morbidity and mortality by at least 25% compared with not offering a screening…
The optimal management of locoregionally advanced NSCLC is evolving. Multimodality treatment is rapidly becoming the most common approach to stage III NSCLC. ASCO guidelines recommend initial chemotherapy (platinum-based, 2 or 3 cycles) combined…
Hypothesis 1: the Groningen ULR and the Provox®2 are the same in terms of the replacement method, the burden on the patient and the convenience of the replacement and of the resistance during phonation. Hypothesis 2: the Groningen ULR has a longer…
The open preperitoneal approach in inguinal hernia repair might have the benefit of a mesh in the preferred space without the disadvantages of an endoscopic procedure.
Implantation of aspheric IOL's results in higher visual performance than spheric IOL's.
Strategies involving shorter and milder ovarian stimulation protocols and single embryo transfer may allow for more IVF cycles in the same period of time, resulting in similar term live birth rate per treatment period despite a minor reduction in…