318 resultaten
Primary objectives of this study: 1. Evaluate the efficacy after 26 weeks of Kuvan® treatment + Phe-restricted diet therapy in increasing dietary Phe tolerance, as compared to dietary therapy alone in <4 year-old infants and children with…
We hypothesize that radiofrequency ablation (RFA) is safe and effective after 5-year follow-up, for the eradication of Barrett's esophagus (BE) containing neoplasia.
[11C]laniquidar has favourable brain and plasma kinetics, and also a small intra-subject variation in humans.
N/A
To assess the effects of treatment in general, and the effects of different types of treatment, doses of drugs, radiation sites and doses, and age at time of treatment on: 1. Ovarian function and actual fertility; 2. Ovarian reserve and (risk of)…
There will be a surplus value of low-threshold day treatment plus caregiver support in the community (LPD-plus CS) compared to regular psychogeriatric day treatment in the nursing home on micro, meso, and macro level. At micro level, it is expected…
The aim of this study is to investigate the possible consequences of generic-generic substitution of gabapentin, a frequently used anti-epileptic drug.
Pelvic floor muscle training has a favorable effect on the symptoms and improves the quality of life of men with LUTS in general practice more than the standard treatment with medication.
We hypothesize that alfentanil will reduce maximum pain score by at least 1.3 point on a 11-point numeric rating scale.
It is expected that the intervention will increase participants' proactive coping skills, which will in turn lead to improved self-care behavior and medical outcomes.
To evaluate if the pregnancy rate, number of ongoing pregnancies and the number of live births after IUI increases as the time between the production of semen and the IUI is shortened.
To assess the efficacy of reducing the sleep time in supine posture with positional therapy using the Z-cushion compared to compared to delay of treatment in patients with mild and moderate positional OSAS.
Patients' favorite volume mouthwash for rinsing is 15ml.
Knee Joint Distraction in comparison with High Tibial Osteotomy in treatment of knee osteoarthritis.
Denuded bone areas are filled up with cartilage (determined with quantitative MRI) which is not anticipated to occur in case of HTO. The cartilage changes are compared two years post treatment.
Local control and toxicity in breast conserving therapy using APBI is not inferior to classical 50 Gy irradiation.
Due to the ageing of the population, the number of (frail) elderly people who suffer from (multi)complex health complaints increases and this ultimately threatens their ability to function independently. Preventive home visitation programmes may…
Changes in synovial inflammation in serial biopsy samples following the administration of tocilizumab in patients with active RA.
Employees that comply to the inclusion criteria and receiving the MPI (Minimal Psychological Intervention), will improve more on scores on depression and fatigue than employees receiving care as usual.
Multiple observational and animal studies suggest a therapeutic effect of bilirubin in various diseases. To verify this suggestion, intervention studies with experimental hyperbilirubinemia are needed. The current study explores the applicability of…
In patients with irreversible corneal endothelial failure, corneal transplantation is the only effective treatment. Currently, the predominant transplantation technique for patients with corneal endothelial disease is Descemet Stripping Automated…