318 resultaten
The Psycho-Education/Coping Skills Training is effective in reducing the negative consequences of stigma in people with a severe mental illness: 1. Increasing quality of life; 2. Improving social functioning; 3. Reducing needs for care.
We hypothesis that early surgical intervention results in less pain over the study period and is more cost-effective than the optimal current step-up practice.
Depression is a major health problem in glioma patients, with emotional, cognitive and physical sequelae. Depression in these patients may be associated with increased morbidity and even with poorer survival. In addition, depression is the most…
The hypothesis to be tested is the relationship between the number of blood transfusions, serum ferritin and transferrin saturation level and MRI T2*Heart, T2*Liver.
A combined physical and face-name training is more effective on cognitive outcomes than the treatments separately.
The current study evaluates whether accurate optical diagnosis of small colorectal polyps (<10mm) in vivo in a non-expert setting can be achieved, resulting in the omission of formal histopathology, which could make colonoscopy more efficient…
This study will test the hypothesis that acute preoperative administration of statins will offer a better protection against MIRI than long term preoperative administration does.
Functional grasping of selected objects from the ARA test (10cm cube, 2.5 cm cube, 6 mm ball bearing and 1,5cm marble) can be improved by combining robotics and electrical stimulation by means of effective self-learning control algorithms.
When the optimal MRI protocol for imaging the sacral plexus and its branching nerves is known, the sacral plexus of children having neurogenic bladder dysfunction due to congenital spinal or sacral anomalies can be imaged. Because not much is known…
To prospectively assess the efficacy, feasibility and safety of a systemised endoscopic surveillance protocol in large multicentre HPS cohort.
We hypothesize that radiofrequency ablation (RFA) is safe and effective after 5-year follow-up, for the eradication of Barrett's esophagus (BE) containing neoplasia.
[11C]laniquidar has favourable brain and plasma kinetics, and also a small intra-subject variation in humans.
Children in the intervention conditions will be more likely to have negative attitudes and norms towards smoking and alcohol than children in the control condition.
There is no difference between treatment with DMSO and prednisolone in reduction of inflammatory signs and symptoms as measured with a validated compound score (ISS) on the severity of CRPS-1.
We aim to compare the effectiveness, feasibility and safety of both metformin and sitagliptin in patients with TIA or minor ischemic stroke and impaired glucose tolerance. We will assess whether a slow increase in dose of metformin and better…
Formalization of the current guidelines on VTE treatment duration with VKA, by means of using a VTE recurrence prediction model in patients with venous thrombo-embolism, will optimize its cost-effectiveness compared to care-as-usual. Only patients…
The purpose of our study is to compare the clinical effectiveness and cost-effectiveness of two treatment strategies of intermittent claudication (IC) due to an iliac artery obstruction: to start with supervised exercise therapy (SET) and deferred…
The first two exons of TRPV1 are deleted in the most common mutation found in cystinosis patients: A large 57 kb deletion. We aim to study TRPV1 expression in cystinosis patients both homozygous and heterozygous for this deletion.
Is hydrocortisone safe and effective in reducing the incidence of the combined outcome death or BPD at 36 weeks PMA in chronically ventilated preterm infants, as compared to placebo.