318 resultaten
To describe the satisfaction of users of fentanyl nose spray to decrease pain.
The current study evaluates whether accurate optical diagnosis of small colorectal polyps (<10mm) in vivo in a non-expert setting can be achieved, resulting in the omission of formal histopathology, which could make colonoscopy more efficient…
iFABP can be used as a primary diagnostic tool to detect and exclude mesenteric ischemia.
We hypothesize VOC signatures to discriminate between critically ill patients: 1. With and without sepsis; 2. With or without pneumonia; 3. With a gram positive or gram negative infection; 4. With and without organ failure, including: A. Acute lung…
When the optimal MRI protocol for imaging the sacral plexus and its branching nerves is known, the sacral plexus of children having neurogenic bladder dysfunction due to congenital spinal or sacral anomalies can be imaged. Because not much is known…
To prospectively assess the efficacy, feasibility and safety of a systemised endoscopic surveillance protocol in large multicentre HPS cohort.
For each of the two treatment arms separately: 1. Null hypotheses (H0): Failure free duration (FFD) at 9 months post allo-SCT = 50%; 2. Alternative hypotheses (H1): FFD at 9 months post allo-SCT = 70%.
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Primary objectives of this study: 1. Evaluate the efficacy after 26 weeks of Kuvan® treatment + Phe-restricted diet therapy in increasing dietary Phe tolerance, as compared to dietary therapy alone in <4 year-old infants and children with…
We hypothesize that radiofrequency ablation (RFA) is safe and effective after 5-year follow-up, for the eradication of Barrett's esophagus (BE) containing neoplasia.
It is expected that dopaminergic antagonism by haloperidol 2mg or 3mg wil result in specific inhibition of both bias and disengagement related activity as measured by EEG in combination with computertasks. Specifically, we expect that, dopamine…
There is no difference between treatment with DMSO and prednisolone in reduction of inflammatory signs and symptoms as measured with a validated compound score (ISS) on the severity of CRPS-1.
Fluorescent near-infrared imaging can assess tissue perfusion in the area of the anastomosis.
Skin temperature can possibly affect the effect of scalp cooling. The primary objective is to search for the possible relation between hair loss and the obtained scalp skin temperature with scalp cooling at a standard temperature.
Early diagnosis of cystic fibrosis (CF) and primary ciliary dyskinesia (PCD) combined with swift identification and treatment of pulmonary infections is important for the preservation of pulmonary function, quality of life and life expectancy. A…
Knee Joint Distraction in comparison with High Tibial Osteotomy in treatment of knee osteoarthritis.
Denuded bone areas are filled up with cartilage (determined with quantitative MRI) which is not anticipated to occur in case of HTO. The cartilage changes are compared two years post treatment.
The software of the PlustoptiX devices is developed for pupils up to 7.8 to 8mm in size. In the study “a double blind randomized study on the efficacy of cyclopentolate 1% and tropicamide 1% in children (MEC nr NL32954.098 /1010-077; NTR 2476),…
Parents will improve their communication- and education skills about alcohol-, tobacco-, and cannabis use.
Our hypothesis is that laparoscopic incisional hernia repair comes with a significant shorter hospital stay compared to open incisional hernia repair.
Patients with T4-irresectable carcinoma are generally treated with definitive chemoradiotherapy without curative intent. Considering the positive results of neoadjuvant chemotherapy followed by surgery, we hypothesize that chemoradiotherapy can…