322 resultaten
The central hypothesis is that the mobile programme is more effective than the web-based programme in increasing physical activity (PA). i.e. 1. Both intervention groups will show an increased PA level. 2. Participants of the mobile programme…
This study has 2 primary objectives: 1) To determine the time point of induction of VEGF expression in the tumour tissue of oesophagus carcinomas during chemoradiation. 2) To determine whether the tumour promoting effects of this induction of VEGF…
To investigate whether patients prefer to be approached by mailed questionnaires for annual follow-up assessment after PCI procedures versus telephone interviews or email-based follow-up
The primary objective is to estimate the frequency of subjects with at least one apnoeic episode, defined as respiratory rate ≤6, detected using the respiR8® device for up to 6 hours after surgery. Apnoea is defined as 10 seconds of no breathing…
We hypothesize that age-related changes in hepatic and intestinal drug metabolism affect the pharmacokinetics of paracetamol.
- The incidence of PONV will be higher in the group receiving dexamethasone alone - There will be no significant difference in the incidence of PONV between the two groups receiving two anti-emetic drugs - There will be less postoperative agitation…
The use of a decision support system will increase adherence to the ESC guideline for atrial fibrillation in terms of calculation of bleeding and stroke risk, and accurate anti-thrombotic treatment for stroke prevention.
We hypothesize that adaptation or tuning of the population PKPD model of propofol will decrease the residual error between predicted and measured plasma-concentrations during maintenance of anaesthesia. The adapted PKPD models can also be used…
Low-molecular-weight heparins (LMWHs) are frequently used in the prophylaxis and therapy of venous thromboembolism (VTE) and the prophylaxis of arterial thromboembolism. LMWHs are mainly excreted by the kidneys and may accumulate in patients with…
With a multi-faceted strategy we are able to implement shared decision making so that it meets the needs and demands of both professionals and patients, without interfering in daily practice.
DMEK is superior to DSAEK in terms of (rate of) VA rehabilitation.
Emotional neglect is a serious social problem, with many adverse consequences for the development of children. However, emotional neglect is difficult to identify for pediatricians. Indicators of emotional neglect in children of parents with…
- The diagnostic accuracy of ultrasound assessment regarding the synovium in patients with haemophilia is > 70%. - Soft tissue changes on initial MRI are associated with osteochondral changes on re-examination after 5 years…
The effects of cross-education on loss of muscle strength and knee function after ACL reconstruction
There is over 30% loss of voluntary muscle force in the operated leg after an anterior cruciate ligament (ACL) reconstruction surgery. Patients could return to sport or work sooner by minimizing muscle weakness. As a novel approach, we propose to…
We hypothesized that adding alimemazine to existing ADHD treatment will decrease ADHD-symptoms as reported by parents and school teachers as well as allergic symptoms.
To dermine the kinetics and spectrum of tumor mutations in the urine and plasma of bladder cancer patients receiving neoadjuvant chemotherapy for locally advanced cancer or systemic therapy for metastatic disease.
We hypothesise a difference in outcome on pain relief in favour of the neurectomy group.
Aim of the study is to receive reference ranges for a plasma and a whole blood thrombingeneration assay.
The main objective is to determine the early and late survival and reoperation outcome of VSARR in patients suffering from aortic root aneurysm with or without aortic regurgitation. Furthermore, we will evaluate the quality of using a SF-36 form.…