357 resultaten
The hypothesis of the TRANSFORM II study is the non-inferiority of Sirolimus Coated Balloon versus Everolimus Eluting Stent in terms of Target Lesion Failure
We hypothesize that clinicians exposed to this intervention are more likely to adopt SDM behaviors than clinicians who do not. A secondary aim is to evaluate whether patients perceive more involvement in the decision-making process.
I. Test whether psychological and psychophysiological indices of PC are differentially affected by fantasizing vs. mindfulness in remitted MDD patients and HC: Pre-and peri-intervention changes will be examined using within-subject and between-group…
3D printed tailormade assistive aids may better fulfill the requirements and needs of clients with disabilities to support them in performing their activities of daily living than the currently available aids or handmade aids provided by…
The aims of this study are validation of PROMs and estimating the minimal important change (MIC) for PROMs and CROs.
Organoids can be cultured from pancreatic ductal biopsies, obtained from chronic pancreatitis patients, to study electrolyte and fluid secretion.
On TRACk, a blended intervention that prepares both patients and pharmacy technicians for two inhaler medication consultations and trains technicians in their communication will improve inhaler medication adherence and inhaler technique in patients…
Primary Objective: • To create a population pharmacokinetic model of SARS-COV-2 neutralizing antibodies as present in ConvP. • To create a population pharmacokinetic model of SARS-COV-2 neutralizing antibodies as present in Nanogam plus Secondary…
Participant demographics affect the health state. TPO-RA treatment affects the severity of symptoms, overall health condition, health state, overall satisfaction with therapy and reasons for discontinuation. TPO-RA treatment affects direct…
COMET measurements are feasible in patients with PAOD and the measurements are tolerable.
1. Disability & Quality of life (descriptive nature, primary analyses) Change in patient-reported outcome variables in overall group (MS diagnosis) and subgroups (CIS, RRMS, SPMS, PPMS) from baseline to 8-year follow-up • Change in…
Transcutaneous blood gas measurements can be used to detect neonatal sepsis.
Lung transplantation patients are immunocompromised due to antirejection therapy. The effectivity of the COVID-19 vaccination in this high-risk patient group is completely unknown.
The main endpoint will be successful sampling and storage of testicular tissue (that is 75% of the samples to be stored for future stem cell preservation will have germ cells). This can be identified based on histological analyses (immuno-),…
none applicable
helicopter transport can be done safe without changes in vital signs
The hypothesis is that methylation marker panel, potentially combined with additional biomarkers, can predict (non-)regression of HGAIN, thus determining the need of immediate treatment versus active surveillance, and the safety of withholding…
We expect an increase in the number of hospitals that have implemented and use a cognitive aid in the OR compared to the number of hospitals in 2018
The primary hypothesis is that local antibiotics are a safe treatment option in the prevention and treatment of fracture-related infections, achieving higher local concentrations without the potential adverse events associated with systemic…
We hypothesize that therapeutic drug monitoring of risperidone in children with an autism spectrum disorder and comorbid behavioral problems will reduce metabolic side effect burden, while retaining clinical effectiveness.