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Health status guided COPD Care (MARCH).

We hypothesize that a treatment algorithm that is based on a simple validated measure of health status (CCQ) improves quality of life (as measured on a separate scale) and other classical COPD outcome measurement parameters such as exacerbation…

A study to investigate the pharmacokinetic profile of 3 doses of sublingual testosterone solution and their effect on physiological and subjective arousal in healthy, sexually functional premenopausal women.

In the present study we will investigate the pharmacokinetic profile of three doses of sublingual testosterone, and measure subjective and physiological measures of sexual functioning in healty premenopausal women. The lowest effective dose of…

Double Dose Treatment: Corticosteroid injection therapy in arthritis.

To determine whether doubling the dose of corticosteroid injections in the treatment of arthritis in knee joints is more effective, both in number of responding patients and in duration of response (pain relief).

Study to explore the effect of a Growing Up Milk with added synbiotics on the intestinal microbiota of healthy Asian toddlers.

A positive effect of the investigational product on the intestinal microbiota of healthy Asian toddlers is expected.

Urological complications after live donor kidney transplantation: Intravesical or extravesical ureterovesical anastomosis?

Our hypothesis is that the extravesical technique reduces the incidence of PCN placement, and urological complications.

Hyperoxic Exercise in Type 2 Diabetes.

Type 2 diabetes patients frequently suffer from physical deconditioning and vascular disease. Although the exact mechanisms are unclear, microvascular changes and endothelial dysfunction appear to inhibit the oxygen transport and uptake in…

BB3 in Kidney Transplantation.

BB3 will improve kidney function in the immediate post-transplant period in patients who have received a DCD kidney transplantation.

Amsterdam Wrist Rules (AWR).

Patients with a wrist trauma represent a substantial part of the patient population at the Emergency Department. Most hospitals routinely carry out a radiological examination of patients following wrist trauma to exclude a distal radius fracture.…

Improving practicality of radiofrequency ablation for eradication of Barrett's mucosa: A randomized trial comparing three different treatment regimens for circumferential ablation using the HALO360 System.

The simplified HALO360 ablation regimen result in an easier and faster ablation procedure, while maintaining efficacy and safety.

N-acetylcysteine in heavy smokers: A double-blind randomized controlled trial.

A four day adminstration of N-acetylcysteine (3600 mg/day) will reduce craving, withdrawal symptoms and the bias towards nicotine related cues compared to a four day administration of placebo in nicotine dependent subjects.

Gerandomiseerde vergelijking tussen indocyanine groen en indocyanine groen gekoppeld aan humaan serum albumine bij intra-operatieve fluorescente beeldvorming van schildwachtklieren bij borstkankerpatienten.

ICG alone without being absorbed to albumin can be used for near-infrared fluorescence SLNB in breast cancer patients.