84 resultaten
Renal transplant patients are at increased risk of colonization and infection with multidrug resistant Enterobacteriaceae (MDRE) due to medications that modify their immune systems, increased healthcare and antibiotic exposure, and surgical…
1. During cold exposure, we aim to stimulate (lipid) metabolism of BAT and muscle tissue. During this cooling process we will perform a two meal test to study the effect of cold exposure on triglyceride metabolism. 2. We expect that after cold…
We hypothesize that aromatase-inhibitors will have lower efficacies in the presence of an abundant estrobolome and high ß-glucuronidase activity. It’s also unclear whether microbiota influences intestinal absorption of tamoxifen’s related metabolite…
We hypothesize that a certain shear load threshold exists, where an increase in the cytokine IL-1a is observed.
We hypothesize that the underlying mechanisms of the varying response in multiple parameters within an individual can be attributed to variability in the causal path between drug administration, drug tissue distribution, and tissue receptor…
We hypothesize that performing a total laparoscopic hysterectomy with same day discharge is safe and leads to equal levels of patient satisfaction when compared to admittance for 1 night.
It is hypothesized that Active+ improves cognitive functioning in elderly with limited mobility through improvements in physical activity. As the literature is inconclusive on characteristics a PA program minimally needs to have in terms of type and…
In the Netherlands, 90% of the patients with gout are managed by general practitioners but most research has been done in secondary care. In primary care there are questions on the clinical relevance of long-term uric acid lowering treatment of gout…
At the end of the study we should be able to publish an internationally accepted, multidisciplinary, evidence based guideline on the management of trigger fingers
PPIs are prescribed very frequently and might cause potentially severe hypomagnesaemia. We carried out a study focussing on the prevalence of hypomagnesaemia in geriatric inpatients using PPI and evaluated risk factors contributing to this effect.…
1, the effect of SLT diminishes in time; how fast does IOP get below target IOP after SLT? 2, is a repeat SLT effective to get/keep IOP under target IOP? 3, is there a racial difference in effect of SLT?
A niche is a defect that can be seen at the site a uterine caesarean section scar. A niche is associated with gynaecological symptoms (abnormal uterine blood loss, dysmenorrhea, chronic pelvic pain) and is related to infertility. Several hormonal…
1) Epidemiology of postoperative pain What is the correlation between pain intensity scores and type of surgical procedure in relation to patient characteristics and analgesia? Is it possible to specify surgical procedures indicating its pain…
It is hypothesized that SADI after sleeve gastrectomy for additional weight loss is superior to a gastric bypass as secondary procedure
Based on our primary results we do not expect anatomical difference between the two groups. However, we expect to see more erosion as compared to 1 year of follow-up.
The aim of this study is to show whether TDM leads to a lower proportion of patients with drug levels below the predefined TDM targets after 12 weeks
Patients undergoing superior capsule reconstructions (SCR) for superior shoulder instability will experience less pain (decrease of at least 2 points) and improved function.
- How effective are the Acts of Kindness exercises with and without reflection compared to an active control condition and wait-list condition on mental well-being, flourishing, positive relations, gratitude, positive and negative emotions, optimism…