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Paravertebral analgesia is associated with superior quality of recovery by achieving comparable pain control whilst having less side-effects.
ARA290 will reduce disease activity in rheumatoid arthritis.
The primary objective is to prospectively identify cardiac damage in childhood cancer patients, during and shortly after treatment with anthracyclines.
We propose that kinase activity profiling may be a potential clinical diagnostic tool to predict for tumor response to targeted therapy with tyrosine kinase inhibitors (TKI's).
The hypothesis is that twins discordant for pregnancy complications display a distinct epigenetic signature in MSCs. This signature contributes to cellular metabolic alterations and is associated with future cardiovascular and neurodevelopmental…
Not applicable
The goal of the proposed study is to test the null hypothesis that vaccination will not boost the cytotoxic T cell responses against UTA2-1 in >20% of the patients.
The pharmacotherapeutic treatment of patients with cancer is generally associated with multiple side-effects. The cause of the side-effects is usually due to the toxicity of the drugs themselves. In addition, drug interactions can intensify side-…
This project aims to investigate the feasibility and oncological safety of eFTR as minimal invasive completion treatment following previous incomplete endoscopic resection of low-risk T1 CRC.
The hypothesis to be tested is that arm B is tolerable and that the outcome in arm B is better than in arm A.
Combining digital FDG-PET/CT and DW-MRI imaging will more accurately predict and define response in rectal cancer patients after neoadjuvant treatment.
In terms of effectiveness, we hypothesized that for each patient during treatment: 1 Compared to a waiting list baseline, the intensive inpatient treatment with adapted ST interventions together with ST milieu therapy during 12 weeks results in…
There are significant differences in the quantitative data for the groups of normally sigthed and visually impaired children older than 6 years. The hypothese is that is also for children from 2 until 6 years.
The pharmacokinetics of erlotinib 150mg QD is comparable to the pharmacokinetics erlotinib 75mg + ritonavir 200mg QD.
Based on recent data derived from animal research in combination with earlier clinical trials, we hypothesize that stimulation of cerebellar nuclei in pediatric refractory epilepsy patients might be effective in significantly decreasing epileptic…
Current frailty screening practice can be improved in specialized burn care
We expect (in the intervention condition as opposed to the control condition): 1. A decrease in children's emotional/behavioral problems and rule-braking behavior; 2. An increase in children's on-task behavior; 3. An increased teacher…
the Aeonose is able to discriminate between patients with Barrett’s esophagus versus patients without a diagnosis of Barrett’s esophagus.
The addition of the EGFR monoclonal antibody Cetuximab to standaard concurrent chemoradiotherapy improves the outcome of treatment of locally advanced non-small lung carcinoma.
The hypothesis is that offering CBT in a group format while discontinuing antidepressant medication will reduce the high relapse rates in remitted anxiety disorder patients who discontinue pharmacological treatment.