286 resultaten
To validate in vivo the velocity offset correction method as published by Walker PG et al. (JMRI 3, 521 1993) such that it can assure velocity offsets < 0.6 cm/s at the ascending aorta and pulmonary artery for 2D through-plane phase contrast…
We hypothesize this difference is due to differences in the mechanisms by which the individuals can withstand and/or adapt to the stress conditions applied in the clinical model and that these mechanisms are of key importance in our ability to…
The aim of the study is: 1. To investigate the benefits and risks of hormonal substitution after prophylactic adnectomy in women with an increased risk for breast- and/or ovarian cancer due to a genetic predisposition; 2. To compare the effects and…
We hypothesise that exercise may reduce risk of breast cancer, either directly or indirectly through a reduction in abdominal fat mass, by favouring the sex hormone profile and decreased insulin. Because the association between breast cancer and…
1. The observation of videos of walking people has a beneficial effect on the amount of physical activity and on physical performance in older adults with dementia 2. The observation of videos of walking people has beneficial effects on cognition…
Prevention of parastomal hernia with a prosthetic mesh in a laparoscopic constructed end-colostomy .
The use of a low weight polypropylene mesh(PPM) in a sublay position reduce the incidence of parastomal hernia in laparoscopic stoma formation.
Hard-core smokers are smokers who have been smoking for many years and who do not intend to quit. This makes them vulnerable to disease and death. Since hard-core smokers are unlikely to quit smoking, before aiming at actually quitting, we first…
We hypothesize that daily oral administration of increasing dosages of Eubacterium hallii, an anaerobic intestinal bacterial strain, can exert beneficial effects on insulin sensitivity and liver fat.
In the Netherlands, case managers play an essential role in the care chain for people with dementia living in the community. Because the profession has just been started, there is a lack of evidence-based practice to provide treatment for agitation…
Compression therapy is not necessary after VNUS. Patients receiving no compression therapy after VNUS will have similar outcomes in post-operative pain, oedema, and HRQOL, post-operative complications, time to full recovery.
For cochlear implanted (CI) patients speech recognition in noise still remains one of the most challenging tasks. One way to improve performance in noise is to benefit from binaural hearing (hearing with two ears). For individuals with residual…
We hypothesize a lung–protective mechanical ventilation using lower tidal volumes during general anesthesia for minimally invasive transthoracic esophagectomy to protect against postoperative pulmonary complications in patients undergoing minimally…
The collaborative care approach is expected to be more effective and more cost-effective compared to care as usual.
Measurement of airways hyperresponsiveness by mannitol (Aridol©) as compared to methacholine saves time to the lung function technician, while being as sensitive to discern hyperresponsive from normo-responsive, and being at least equally acceptable…
Adherence to diabetes guideines is moderate, especially on educational aspects. Changes in lifestyle is a major element of the patient treatment. Studies on motivational Interviewing show promising results among dieticians. There are no primary care…
We hypothesize that systemic aPC will benefit patients with ALI/ARDS, as caused by inflammatory as well as infectious disorders, in terms of gas exchange, edema and capillary leak in these lungs, as well as in ventilator-days (duration of mechanical…
There is a clinically and statistically significant difference in the percentage of patients who achieve and maintain clinical remission (defined as DAS < 1.6) and in functional ability and progression of radiological joint damage after 1…
Nasotracheal intubation is a frequently employed intubation technique, but passage of the tube through the nasal cavity may lacerate the mucosa, and create a fausse route. In the present study we therefore aim to evaluate whether a new strategy that…
Correction of sub-clinical prolongation of coagulation tests (i.e., PTT between 14.7 – 20 seconds and platelets < 100 x 109/L) and transfusion of platelets in patients with Ascal®, significantly decreases the incidence of clinical significant…