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OBJECTIVE: To evaluate the immediate and longer-term effects of early cognitive rehabilitation on cognitive performance and self-reported symptoms/functioning in patients with low-grade gliomas and meningiomas, in a prospective randomized trial.…
We hypothesize that the exposure to inulin will strengthen the resilience of the oral ecosystem such that 1) it will be able to withstand experimental gingivitis challenge by maintaining a more health-associated microbiome during this challenge and…
We hypothesize that our integrated care intervention, as compared to usual care and a placebo version of the m/eHealth intervention, will increase quality of life of KA patients by improving societal participation including work, indirectly reducing…
Daily showering followed by immediate application of emollient is better for the clinical outcome of mild to moderate AD in children, when compared to once weekly showering followed by immediate application of emollient.
The hypothesis is that the metabolic age, representing a health score will be lower after nine weeks of personalized dietary intervention compared to the control arm (without dietary advice). The phenotypic flexibility or resilience (the ability to…
In line with a previous pilot study we hypothesize that 3MDR will significantly decrease PTSD symptom severity in treatment resistant veterans with chronic PTSD in comparison with treatment as usual.
We hypothesize that iABM patients, relative to controls, will show less addiction problems, increased health, reduced physical and psychological complaints, and reduced use of health care post-intervention and at 6 & 12 month FU Further, we…
The level of AGEs can predict response to intravitreal anti-VEGF therapy in DME
With this study we aim to disentangle mindfulness and placebo effects on stress. We investigate how decentering (a core active component of mindfulness) and positive treatment expectations (a core component of placebo effects) interactively…
we hypothesize that paediatric patients with per-operative rhinovirus positive Polymerase Chain Reaction (PCR) testing have a longer paediatric intensive care unit (PICU) admission , compared to children who test negative.
(1) We hypothesize that participants in the intervention condition will have smoked less tobacco cigarettes (adjusted for baseline measurements) in the past 7 days at 6-month follow-up compared to participants in the control condition. (2) We…
Adding specific components designed to target three risk factors for child maltreatment (parental stress, parental anger, and post-traumatic stress symptoms) to an evidence-based home visiting program alleviates these specific risk factors.
It is hypothesized that the lotteries will increase abstinence smoking rates over and above an effective smoking-cessation training program.
Implementation of a practice guideline for optimal symptom relief in Dutch nursing homes will reduce suffering in patients with dementia and pneumonia.
Self-directed learning is a more effective learning method than directed learning to teach a new motor skill to children aged 9 to 11 in mainstream education. Regardless of the skill level.
Based on Faber ea. 2006, we expect that the effectiveness of ‘In Balans’ can be replicated and extended in a group of community-dwelling pre-frail and non-frail older adults with an increased risk of falls, with a significant reduction of the number…
The anterior approach will result in a faster postoperative recovery and will be more (cost-) effective
The primary objective of this study is to reduce the number of patients with at least one event when using the CRR (a computerised clinical descion support system) compared to the regular care. These events consist of hospital referrals, delirium,…
We hypothesize the MBPS knee device to have superior range of motion (and therefore PROMs) 1 year after surgery compared to the MB knee device.
To assess the safety and efficacy of endovascular renal nerve ablation in patients with systolic heart failure.