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That laparoscopic surgery alone or in combination with fast track perioperative care is to be preferred over open surgery with standard care in patients having segmental colectomy for malignant disease.
It is hypothesized that conversion to a regimen with sirolimus, an effective immunosuppressive drug with antiproliferative properties, could diminish the recurrence rate of cutaneous SCC. The potential usefulness of sirolimus in the prevention of (…
Intravitreal injection of vancomycin 0.2 mg, gentamycin 0.05 mg, and dexamethason diphosphate 400 mg reduces tissue damage in patients with bacterial endophthalmitis.
Dexamethason reduces the rate of detubation failure in children at risk.
The hypothesis of this study is that the new opioid remifentanil will provide less side-effects and better painrelief during labour, than the conventional opioids fentanyl and pethidine.
Active treatment of acute gouty arthritis by a short course of oral prednisone or naproxen are equal.
Rivastigmine is as effective in the treatment of delirium as Haloperidol.
An intervention with a fortified drink containing iron, zinc, vitamin A, vitamin C, folate, vitamin B-12 and B-6 and/or omega-3 polyunsaturated fatty acids over one year can improve cognitive performance in Australian well-nourished children and…
Nosocomial Staphylococcus aureus infections in S. aureus nasal carriers can be reduced by 50%, by application of mupirocin nasal ointment in combination with washing with chloorhexidin containing soap within 24 hours after admission.
Treatment with probiotics can alter the allergen-specific in vivo or in vitro immunological response in food-allergic children.
Prebiotics are present in breastfeeding and thusfar not in premture formula, we presume that adding prebiotics to premature formula, will be well tolarated, result in more loose stools compared to regular premature formula and will be responsable…
Can allogeneic red cell transfusions for preterm/very low birth weight newborns be reduced and is this associated with favourable outcome of usual neonatal complications (infections, cerebral bleeding , duration of assisted ventilation and death)…
The main aims of the POBASCAM trial are to find out whether the efficacy and cost-effectiveness of the cervical screening programme can be improved by increasing the screening interval for women with normal cytology and a negative hrHPV test, and by…
The specific aim in the current study is to evaluate if the use of the insulin lowering agent metformin in polycystic ovary syndrome (PCOS) has effect on micro- and macro circulation.
Intraventricular infusion of rt-PA reduces the frequency of poor outcome (death or dependency) in patients with a severe intraventricular haemorrhage after aneurysmal subarachnoid hemorrhage.
This study is designed to get a full PK/PD characteristic of the opioid analgesic morphine and its active metabolite M6G after oral and iv infusion and to test wether sex differences exist in the analgesic behaviour of both opioids.
To determine the efficacy of quetiapine as an adjunct to patients with OCD, without comorbitity, who are newly diagnosed, medication-naive or free. The following hypotheses will be tested: 1. Addition of quetiapine to a SRI increases the number of…
The study hypothesis is that that daily oral atamestane (100 mg/day), dehydroepiandrosterone (50 mg/day) alone and the combined regimen improve physical frailty, muscle strength and functional performance compared to placebo.