556 resultaten
The proposed study aims to investigate a novel peri-operative PK-guided dosing strategy, which is expected to reduce FVIII consumption and costs by minimally 25%. Moreover, the five participating hospitals will gain experience with PK-guided dosing…
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We hypothesize: (a) that providing patient specific risk information to elders when they visit the emergency department will improve their willingness to visit the FOC; and (b) that elders may underestimate their risk for a recurrent fall.
1. To determine the effectiveness of 2 interventions (basic support (A&Cb) vs intensive support (A&Ci) compared to care as usual in CHF patients on time to first major event (HF hospitalisations and death), quality of life and costs…
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The efficacy of transluminal drainage of pancreatic fluid collections may be increased by creation of a larger fistula than currently possible with placement of multiple plastic endoprostheses.
The aim of the study is to investigate the interrater and intrarater reliability of the MicroFET5 inclinometer for movements of the lumbar spine specific flexion, extension and lateral flexion. The hypothesis is that the MicroFET5 inclinometer is a…
To evaluate the incidence, risk factors and perinatal morbidity and mortality due to CA after TTTS treated with fetoscopic laser surgery
The study aims to assess the efficacy (in terms of growth response over the years of treatment, including final height) and safety of a treatment regimen consisting of: 1. Authentic biosynthetic growth hormone (GH) in a dosage of 4 IU/m2/day between…
308-nm Excimer lasertherapy will obtain faster repigmentation after minigrafting than NB-UVB therapy in vitiligo patients.
We expect that there will be a difference in energy intake after 2 weeks of supplementation of a bar with 10g added fibre out of chirory root pulp (CRP) compared to 2 weeks of supplementation of a control bar. We hypothesize that the energy intake…
An online intervention will be an effective intervention for treating affective symptoms in pregnancy and their complications by reaching more women and making therapy easier accessible
In the RIO study programme, the efficacy of rimonabant was examined. The next step is to assess the use of rimonabant, its safety and effectiveness in daily practice. In daily practice people also have other diseases, may use other medication and…
Primary: are there differences between the online course group and the control group in the change in depressive complaints from baseline to follow-up measurements? Secundary: Is the intervention cost-effective compared to a no preventive…
Several open-label pilot studies have shown a promising effect of intrapyloric botulinum toxin injection on symptoms in severe gastroparesis. However, data from randomized, double-blind, placebo-controlled studies are not yet available. We intend to…
DBS in the nucleus accumbens can lead to long-term improvement of obsessive-compulsive symptoms and funtioning, without unacceptable side-effects.
To assess the effect of an Amino Acid based Formula (AAF) with synbiotics on the balance of major constituents of the gut microbiota, specifically Bifidobacteria vs. Clostridial groups.
The Solace European Confirmatory (SOLECT) Trial is designed to determine whether the Solace Bladder Control System is safe and effective for the treatment of Stress Urinary Incontinence (SUI) in adult females.
The knotted grip placement technique of proseal laryngeal mask shall ease its placement in patients undergoing general anesthesia for elective surgeries.