571 resultaten
In the present placebo controlled study we will investigate the influence of valence on attention when viewing visual erotic stimuli. Especially when under the treatment condition of testosterone with sildenafil. In addition, we will investigate the…
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SLE patients show a decreased humoral immune response to influenza vaccination, as compared to healthy controls. Furthermore the use of immunosuppressives is of influence on vaccination immunogenicity, it has been demonstrated that the use of drugs…
The self-help intervention Happy@Work will reduce symptoms of depression. The self-help intervention Happy@Work will be cost effective.
The hypothesis to be tested is that arm B is tolerable and that the outcome in arm B is better than in arm A.
Obtain transient temperature data of the skin, core and wound surface during orthopedic back surgery in order to validate the numerical model of Severens for this type of surgery.
We hypothesize that peripheral perfusion targeted fluid management (PPTFM) might prevent excessive fluid administration, leading to less formation of tissue edema, less respiratory dysfunction and shorter duration of mechanical ventilation.
The purpose of the study is to conduct a randomised controlled trial with the onlinecourse 'Voluit Leven' as an intervention to study the: 1. Cost-effectiveness in terms of reduction of psychological symptoms (mood symptoms and disorders…
We want to establish an abbreviated, multidimensional, evidence based, diagnostic personalityprotocol within the mental health services. The hypothesis is that the mutidimensional testcombination of VTCI, NEO-FFI and CISS is sufficient reliable and…
A constant Hb concentration will improve the quality of life of patiënts with a chronic need for bloodtransfusions.
Interferons (IFNs) are a family of cytokines which have important antiviral and antiproliferative properties. They also play an important role in immunomodulation. Type I IFNs have been implicated in autoimmune diseases, including systemic lupus…
This is a superiority trial testing the hypothesis that adenoidectomy is more effective than a watchful waiting strategy in children with recurrent upper respiratory tract infections.
ETMI increases the detection rate of early neoplasia in BE patients with 40% or more compared to standard video endoscopy
The primary objective of this study is to demonstrate that contact isolation of patients colonised with ESBL-producing Enterobacteriaceae in a multiple-occupancy room is not inferior to contact isolation in a single-occupancy room with respect to…
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The aims of this study are twofold: 1. Examine the effectiveness of the web-based CBT self-help intervention for MS-patients with depressive symptoms; 2. Compare characteristics of symptoms of depression and anxiety, quality of life and perceived…
The aim of this study is to investigate the effectiveness and the cost-effectiveness of the individual CBT program the “D(o)epressie cursus” by means of the following hypotheses; 1. Is the individual CBT program the “D(o)epressie cursus” more…
An educational film seen before surgery change the postoperative expressed need for opioids by the patient (i.e., increase when postoperative patients report NRS > 4 and decrease when patients report NRS ≤ 4).
Glucose control by closed loop in diabetes type 1 is equal to glucose control by insulin pump.
To evaluate the impact of three different implementation strategies for implementing IBSM in current clinical practice, we have proposed the following three hypotheses: 1. Hypothesis 1 (Reach): More general practices will participate in IBSM in the…