664 resultaten
We hypothesize that propofol combined with ketamine has a optimal physician’s satisfaction, patient’s satisfaction and hemodynamic stability, in comparison with propofol combined with either alfentanil or remifentanil.
The objectives is to clarify what the distribution and interrelation is of relevant clinical microbial, biochemical and immunological parameters of the oral ecosystem in a systemically healthy (non diseased) young adult population. Such biodata…
Whole Body Vibration (WBV) applied via a chair has positive chronic effects on cognitive function of older people.
Ventilation-associated pneumonia (VAP) is an important complication in intubated mechanically ventilated patients. VAP is associated with a substantial increase in morbidity, mortality, and cost. One of the most relevant causes of VAP is passage of…
We hypothesize that in rheumatoid arthritis (RA) patients responding to adalimumab, with high adalimumab serum concentrations at least 28 weeks after treatment initiation: 1. Lowering the serum concentrations through dose interval prolongation will…
We hypothesize that the CPA Talking-with-children-intervention will have a beneficial effect on the mental health and quality of life of maltreated children. We expect that children who participate in the CPA investigation (CPA Talking-with-…
It is expected that the urinary and serum level of intestinal fatty acid binding protein (I-FABP) and the urinary level of Claudin-3 have prognostic relevance for early identification of patients at risk for intestinal ischemia-related morbidity or…
Patients with a BMI > 30 kg/m2 in the ICU have a higher incidence of pressure ulcers and wound infections in the ICU compared with patients with a BMI 18-25kg/m2. They develop them sooner during admittance and the severity and time to…
Patients who will train with the SCRIPT-system will have similar or improved arm and hand function in comparison with the patients who receive conventional arm and hand exercises.
The aim is to investigate the effects, costs, and feasibility of an evidence-based professional-directed implementation strategy to implement the Dutch peri-operative guidelines, i.e. to achieve a higher adherence to these guidelines. It is…
Use of IBD-live for 1 year: 1. Reduces the relapse rate from 40% to 25%; 2. Increases quality of life (assessed with the IMPACT-III questionnaire).
When this new knee system will facilitate a high knee flexion, this will be depicted in a superior knee function. In addition, a high flexion ability will result in high clinical and functional outcome scores and high patient satisfaction.
Een "systeem biologische aanpak" kan nieuwe diagnostische markers en oorzakelijke immuunprocessen identificeren bij patiënten met artritis psoriatica.
A high protein diet and resistance exercise have a positive effect on fat free mass, fat mass, muscle strength, physical functioning and quality of life compared to regular dietary and exercise advice according to CBO guidelines for treatment of…
We hypothesize that in patients with severe corticosteroid dependent asthma Dabigatran etexilate will: 1. Reduce airway inflammation; 2. Improve asthma control and pulmonary function; 3. Reduce hypercoagulability in the airways.
We hypothesize that group medical appointments will enhance adherence to treatment and self-efficacy in patients with sickle cell disease, as well as increase quality of life, and satisfaction with the treating physician and nurse. When performing…
The aim of the pilot trial is to: 1. evaluate the potential effectiveness and effect size of the e-support program for parents of children with a chronic kidney disease; 2. to identify outcome measures most likely to capture potential patient…
If not well treated rheumatoid arthritis (RA) can lead to severe joint damage and subsequently functional impairment. Current treatment strategies aim at quickly lowering disease activity in order to prevent later damage. RA treatment…
The main hypothesis is that normo-ovulatory women with a deleterious BRCA mutation have lower levels of AMH compared to normal controls, with at least a difference of 0.90 ng/ml, suggesting an effect size of approximately five years in menopausal…