746 resultaten
An online intervention will be an effective intervention for treating affective symptoms in pregnancy and their complications by reaching more women and making therapy easier accessible
OR workflow for surgeons needing to interact with the laparoscopic equipment during surgery is optimized using TedCube© in combination with the Myo™ gesture control armband and/or a wireless headset.
A safe RP2D of Vyxeos®/CPX-351 in combination with clofarabine can be identified in this phase 1b study.
Benign liver tumors and cysts carry a significant burden on the quality of life in some cases. Apart from impairing symptoms, psychological burden might provide sufficient ground for surgical intervention. There is a variable approach to them…
Primary: are there differences between the online course group and the control group in the change in depressive complaints from baseline to follow-up measurements? Secundary: Is the intervention cost-effective compared to a no preventive…
We hypothesize that in critically ill patients, measuring the anti-factor-Xa randomly in a 3 to 5 hours timeframe, may introduce a significant variation in the measured anti-factor-Xa and can seriously underestimate the real peak anti-factor-Xa.
A 12 weekly computer-tailored coaching program reduces sedentary behavior. Perceived bodily pain, mental health, vitality, stress, and performance are expected to lower by the means of reduced sitting time.
Trifluridine is primarily metabolized through degradation by thymidine phosphorylase to the inactive metabolite 5-(trifluoromethyl)-uracil (FTY) without any involvement of the cytochrome P450 enzyme system. The primary route of excretion of…
Exploratory study investigating the efficacy of the currently recommended dosing regimen of ciprofloxacin prophylaxis in patients treated for haematological malignancies.
Objectives Primary: To examine the effects of regular glucose lowering treatment on inflammatory markers in type 2 Diabetes Mellitus Secondary: To identify markers/fingerprints that predict the response of a patient to glucose lowering therapy in…
Fiducial markers placed on endoscopically determined tumor borders are a good surrogate for macroscopic tumor.
We aim to test the hypotheses that offering additional online adaptive coaching to a web-based self-management program will be more effective than a web-based self-management program without coaching in terms of self-management behaviour without…
Endocuff colonoscopy will increase the number of adenomas detected.
We hypothesize that dietary supplementation with seaweed will improve glucose regulation in T2DM patients.
It is an observational study, no null hypothesis has been formulated. The purpose of StEM is to understand the expectations, needs, experiences, choices and decisions of pregnant women and women who recently gave birth in the Netherlands, recording…
High-resolution ultrasound (HRUS) is a quick and cost-effective technique to study the morphology of peripheral nerves. Sonographic characteristics of plexiform neurofibromas and MPNST have been described in the literature. Recently, a pilot study…
Main question: Is Theraplay an effective treatment method for children with ASD and what is the effect of treatment with Theraplay on their parents? Prior RCTs proved that Theraplay leads, among other things, to a decrease in internalizing problem…
Awake craniotomy improves safety and efficacy during surgery for glioblastoma in eloquent areas
we would like to investigate whether multiple fecal transplantations using either allogenic (lean preferably vegetarian/vegan donor) or autologous (own) donors have a beneficial effect on non alcoholic steatohepatitis (NASH) using biopsy and MRI…
We hypothesize that DVT can be safely ruled out by the LEFt rule in combination with the D-dimer test in 5-10% of pregnant women, and that a normal MRDTI safely rules out isolated pelvic vein thrombosis. We hypothesize that 7-10% of performed MRDTI’…