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OR workflow for surgeons needing to interact with the laparoscopic equipment during surgery is optimized using TedCube© in combination with the Myo™ gesture control armband and/or a wireless headset.
A safe RP2D of Vyxeos®/CPX-351 in combination with clofarabine can be identified in this phase 1b study.
Benign liver tumors and cysts carry a significant burden on the quality of life in some cases. Apart from impairing symptoms, psychological burden might provide sufficient ground for surgical intervention. There is a variable approach to them…
the correspondence between orosensation of sweetness and post-oral sensation of calories influences resting energy expenditure, cerebral blood flow and gastric emptying, and more specifically that the “not sweet enough” beverage, that contains more…
The aims of the study are: To investigate the short-term effectiveness of antecedent and consequent behavioral teacher training techniques for teachers of children attending regular primary school (class 3 to 8, six to thirteen years old) with (…
We hypothesize that in critically ill patients, measuring the anti-factor-Xa randomly in a 3 to 5 hours timeframe, may introduce a significant variation in the measured anti-factor-Xa and can seriously underestimate the real peak anti-factor-Xa.
A 12 weekly computer-tailored coaching program reduces sedentary behavior. Perceived bodily pain, mental health, vitality, stress, and performance are expected to lower by the means of reduced sitting time.
Cabazitaxel is a tubulin-binding taxane drug that improves survival of patients with docetaxel-metastatic-castration-resistant prostate cancer (mCRPC). Unfortunately, cabazitaxel is not effective in all patients and can have serious side effects.…
The Untire app will create awareness by proving psycho-education and will give insight in ones’ energy levels, ones’ thoughts and behaviors in relation to energy levels and provides exercises that help users to challenge ineffective thoughts and…
Trifluridine is primarily metabolized through degradation by thymidine phosphorylase to the inactive metabolite 5-(trifluoromethyl)-uracil (FTY) without any involvement of the cytochrome P450 enzyme system. The primary route of excretion of…
Exploratory study investigating the efficacy of the currently recommended dosing regimen of ciprofloxacin prophylaxis in patients treated for haematological malignancies.
Fiducial markers placed on endoscopically determined tumor borders are a good surrogate for macroscopic tumor.
The primary hypothesis of the study is that a well-being intervention (‘This is your life’) offered to bipolar disorder (BD) patients in remission in addition to usual care (CAU) is more (cost-)effective than CAU only.
The aim is to examine the natural course of Acute Stress Disorder (ASD) symptoms (aim 1) and the effects of these symptoms on the development of Port-Traumatic Stress Disorder (PTSD) and patients¡¯ psychological distress (i.e., anxiety and…
The hypothesis is that STEMI patients who are pre-treated with crushed ticagrelor and paracetamol have a higher level of platelet inhibition after primary PCI than patients pre-treated with crushed ticagrelor who are treated with fentanyl.
We hypothesize that dietary supplementation with seaweed will improve glucose regulation in T2DM patients.
This overall study aims to evaluate the effects of cardiology PC+ centre on the Triple Aim outcomes. The underlying premises of the researchers on the effects of the intervention are that the cardiology PC+ centre will result in an (at least)…
It is an observational study, no null hypothesis has been formulated. The purpose of StEM is to understand the expectations, needs, experiences, choices and decisions of pregnant women and women who recently gave birth in the Netherlands, recording…
High-resolution ultrasound (HRUS) is a quick and cost-effective technique to study the morphology of peripheral nerves. Sonographic characteristics of plexiform neurofibromas and MPNST have been described in the literature. Recently, a pilot study…
Main question: Is Theraplay an effective treatment method for children with ASD and what is the effect of treatment with Theraplay on their parents? Prior RCTs proved that Theraplay leads, among other things, to a decrease in internalizing problem…