107 resultaten
It is hopthesized that a multidimensional implementation approach with multiple interventions integrated in the usual care will improve physical behaviour during hospitalization
We hypothesize that the amino acid loss in the dialysate during a routine HD session in the MUMC+ will be between 8-12 g/session, resulting in a significant decline in plasma free amino acid concentration.
Firstly, it is expected that workers who get a single component intervention will sit less at the workplace compared to workers in the control condition (H1). In addition, we expect there will be differences between the three intervention conditions…
The hypothesis is that macroalbuminuria could be a proxy for early changes to the vascular wall in T2D patients and therefore could be an early clinical indication of accelerated vascular ageing. Therefore, there is a clinical need to early identify…
A personalized, individual face-to-face program ’Managing Fatigue’ is effective to improve participation in people with FSHD or MM who experience chronic fatigue.
Postoperative change in deltoid volume following reverse shoulder arthroplasty is related to functional outcome
Gut-homing lymphocytes play a role in the development and maintainence of perianal fistula in Crohn's disease patients.
Crohn’s disease (CD) is a chronic inflammatory bowel disorder (IBD) with a major impact on quality of life. Mucosal healing is an important treatment outcome to prevent long term complications of the disease. Regulatory M2 type macrophages play a…
Our primary objective is to compare the short and medium term (up to 6 months) clinical results in pain and function of the Bauerfeind SecuTec OA brace with only conservative treatment (no brace) in the management of patients with medial knee OA and…
We hypothesize that depletion of carnitine occurs during infusion of oxaliplatin, due to increased renal loss. This secondary carnitine deficiency may contribute to the development of CIPN.
It is hypothesised that compared to waiting list control condition, participants in the intervention improve their diet and physical activity on the short (6 months after baseline) and long-term (12 months after baseline; when the participant…
Group receiving Friso Comfort Next (with milk fat and mixture of different length prebiotics) will have a lower % of all hard stools reported during the 2-mo study period compared to another Young Child Formula (with partially hydrolysed whey…
The dutch language version of the PRHWE and the Quick DASH questionnaire are valid to use in patients with hand and wrist complaints
The absolute bioavailability of oral imatinib (Glivec®) at steady state can be calculated using LC-MS/MS after concomitant administration of a single 100 µg microdose of stable isotope labeled imatinib (imatinib-d8).
The hypothesis states that the time tom complete an emergency airway with Cricath device is significant faster than with Quicktrach device, which will be studied on porcine cadaver models. In the second outcome, the hypothesis states that there is…
Our hypothesis is that piperacillin/tazobactam, ciprofloxacin, co-trimoxazole and doxycycline are able to penetrate hepatic cysts.
We hypothesize that breast cancer organoids will result in a prospective clinical model that is predictive of treatment response.
We hypothesize that early mobilisation followed by additional protein intake is more effective in preservation of muscle mass than early mobilisation and optimal nutrition separately.
The CPCHILD-18+ is sufficiently tested for its psycometric characteristics to be used in clinical practice and research