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1) Implementing TIPP will prevent acute emergency room (ER) visits, rehospitalisations and inappropriate referrals 2) Implementing TIPP improves transitional patient safety culture 3) Although TIPP aims at reducing transitional incidents,…
About 25% of patients who suffer from a subarachnoid hemorrhage or intraventricular hemorrhage have a vital indication for an external ventricular or lumbar drain to aleviate the intracranial pressure. About 5-10% of these patients develop a…
The present mode of (tonic) SCS is accompanied by paraesthesia in the area of stimulation. Recently, a new mode of SCS has been developed which makes it possible to apply spinal cord stimulation without paraesthesias. This mode is called burst…
A positive effect of a Growing Up Milk with added prebiotics or prebiotics and LCPUFA on the intestinal microbiota of toddlers.
Otosclerosis is an isolated ear disorder which can cause hearing and balance impairment. The cause of these symptoms is a disturbed bone metabolism confined to the area of the otic pit, the embryologic predecessor of the inner ear. Most patients…
This study will use a Randomized Controlled Trial (RCT) to evaluate the effectiveness and underlying mechanisms of the video game Mindlight, a newly developed anxiety-reducing training for children. Mindlight and a control game will be played for…
Usage of the 'Moveosiphon' sonothermal sink disinfection device prevents leads to a persistant decrease in colonization with multiresistant Pseudomonas aeruginosa
It is hypothesized that the behavioral effect (i.e. slower RT and impaired attention) of a non-sedative antihistamine will be apparent in combination with a Pgp-blocker, but will not be apparent when administered alone. This, because when a non-…
Blended eHealth treatment is evenly effective and more cost-effective than treatment as usual.
The application of contrast-enhanced ultrasound can accelerate thrombolysis in patients with acute peripheral arterial occlusions.
Whereas initially the concept of burn-out was restricted to professions in the human services domain, over time the scope has been broadened to all sorts of professions and occupational groups (Schaufeli et al., 2002). Research indicates that full…
Brown adipose tissue (BAT) is thought to be involved in human glucose and lipid metabolism, however the mechanisms by which this adipose tissue is activated remain to be elucidated. Recent data in db/db mice have suggested that oral butyrate has…
1) FeNO, blood eosinophils and total IgE will have a moderate diagnostic accuracy to detect sputum eosinophilia in adult-onset asthma patients. 2) There will be differences in accuracy between sub-groups of patients.
Electrophysiological connectivity between ATN and cortical zones involved in the epilepsy of the patient in question relates to treatment response
To assess the current indications for HPS greenlight laser treatment and the treatment outcomes in terms of objective and subjective improvement.
Taken together, a profound understanding of the [18F]FDHT pharmacokinetics could lead to an optimization of the [18F]FDHT PET diagnostic potential; integration of DCE MRI and PET parameters would allow for a clinically feasible method with PET-MRI.…
The hypothesis is that modarate and late preterm infants at age 12 reported more symptoms consistent with asthma and use more asthma medications, as well as a poorer lung function, exercise capacity and Lung Clearance Index than healthy peers.
The effectiveness of the commercial video game Journey in preventing depression will be tested in a Dutch sample of adolescents with elevated depressive symptoms. In an RCT design the effectiveness of Journey will be compared to the effectiveness to…
Major depressive disorder (MDD) is projected to rank second on a list of 15 major diseases in terms of burden and is highly recurrent in nature. Accordingly, efforts to reduce the disabling effects of this chronic condition should shift to…