57 resultaten
Background: Injury rate and injury severity of elderly cyclists due to self-induced cycle accidents increase with age. Starting at the age of 55 years, injury risk increases with a factor 4 at the age of 75 years. Injury mechanisms such as slippery…
Combination therapy with telaprevir/ ribavirin is as effective as the current standard of care with peginterferon-alfa/ ribavirin for the treatment of acute Hepatitis C in HIV-infected individuals.
Our hypothesis is that custom made insoles and a home-based exercise program would be superior to a home-based exercise program alone at 12 weeks follow-up.
In adult congenital heart disease patients with exercise-induced pulmonary arterial hypertension, treatment with bosentan lowers the mean pulmonary arterial pressure, which may result in improvement of the cardiopulmonary circulation,…
Is a prevention program, based on principles of health behavior change, education about playing-related musculoskeletal disorders and postural training, more effective in preventing and/ or reducing disabilities from musculoskeletal complaints in…
The hypothesis is that rhGH treatment in children with KS results within 6 weeks in a change of metabolism recognizable as an increase of total energy expenditure (TEE). This change in metabolism can be used as a predictor of growth response in the…
It is hypothesized that a low protamine-to-heparin ratio leads to improved hemostasis after cardiac surgery with cardiopulmonary bypass as compared to a high ratio as measured by rotational thromboelastometry, and reduces postoperative blood loss…
The hypothesis is, when adolescents are screened for problems at an early stage and do get help, they will be less absent from school and will have less psychosocial problems.
Antipsychotics (haloperidol) can cause acute changes in cardiovascular functions, metobolic parameters and platelet aggregation in elderly patients.
The primary objective of this study is to analyse whether preventive hamstring exercises (Nordic Hamstring Curl) can reduce injury incidence in Dutch elite amateur soccer players. The secondary objective of this study is to analyse whether…
In patients with side effects, during VNS, there is: 1. A decrease in lung function parameters; 2. A reduced increase in heart rate; 3. A reduced increase in blood pressure.
The implant stability for the GTS is equal to the Taperloc in the initial two years and also thereafter. Focus will be on proximal or distal migration of the centre of the stem, migration of the tip, wear and survival.
To investigate whether the addition of preoperative radiochemotherapy to the standard treatment, consisting of explorative laparotomy, pancreaticoduodenectomy if possible, followed by adjuvant chemotherapy, improves the overall survival (analyzed by…
Recurrent miscarriages is defined as three or more consecutive miscarriages prior to the 20th week of gestation. Whenever the diagnosis ‘recurrent miscarriages’ is established, an underlying cause may be identified in about 25-50% of cases. A…
Despite good results of primary total knee arthroplasty (TKA) the number of revision total knee arthroplasties (rTKAs) is rising and a further increase is predicted. rTKA is a more complicated surgical procedure compared to primary TKA and leads to…
General: The transfer-oriented version of HSD, in comparison to the regular version, will have larger and more durable effects on substance use behaviors and their determinants and will have favorable effects on behavior and determinants in four…
1. A treatment program with attentional control training (MBCT) leads to significant more reduction in anxiety- and moodsymptoms and significant more experienced mental health than the regular treatment form; 2. There is a positive correlation…
Rituximab (antiCD20) in association with chemotherapy has extended the survival of adult patients with diffuse large B-cell lymphoma (DLBCL). Also in adults, there is accumulating evidence of a benefit of Rituximab for Primary mediastinal large B-…
Using low field stimulation on two brain regions simultaneously, we aim to specifically alter the connectivity between one or more pairs of brain areas.