Zoeken naar een onderzoek

Effectiveness of www.SnelBeter.nl: activating occupational care on-line in employees with sickness absence due to back or neck pain.

Many employees who are sicklisted do not really know how to handle the situation. Simple and specific education and individually based instructions through a website can possibly solve or reduce this problem. Besides, the website contains a…

A comparison of once daily insulin detemir given pre-breakfast or bedtime, according to need, with bedtime insulin glargine in people with type 2 diabetes characterized by an asymmetric insulin requirement across the day and night.

Insulin detemir, when injected once daily at an individually appropriate time (either before breakfast or at bedtime), provides superior glycaemic control to insulin glargine injected indiscriminately at bedtime in patients that had clearly…

Closed Reduction vs ORIF vs Non-Operative Study of intra-articular calcaneal fractures.

Percutaneous, ORIF and conservative treated of displaced intra-articular calcaneal fractures have a similar outcome as measured with the AOFAS (American Orthopaedic Foot and Ankle Society) score.

The Effects of Epidermal Growth Factor (EGFR) Inhibition on Pulmonary Arterial Hypertension Associated with Systemic Sclerosis.

As EGFR plays a role in pathogenesis of both pulmonary arterial hypertension and systemic sclerosis, EGFR inhibition will lead to beneficial effects in disease course.

Effect of intravenous fluid restriction on hospital stay and complications after abdominal surgery: a randomised triple-blinded clinical trial.

A restrictive fluid regimen is beneficial for postoperative recovey after abdominal surgery, as to hospital stay and postoperative complications.

rt-PA administration by retinal branch vein route for Central Retinal Vein Occlusion (CRVO). A Randomized - Conventional Therapy controlled – Trial.

rt-PA administration by retinal branch vein way in CRVO patients improves final BCVA.

NOSTRADAMUS: Testing for thrombophilia in patients with a first episode of venous thromboembolism (VTE): a randomized controlled trial to assess effects on clinical outcomes, quality of life, and costs.

Testing for thrombophilia after a first episode of VTE with subsequent prolongation of anticoagulant treatment in thrombophilic patients is beneficial in terms of clinical outcomes, quality of life, and costs.

Dexamethason for the treatment of exacerbations in multiple sclerosis.

In this double-blind randomized controlled trial, we would like to show that a five-day treatment course with 16mg/day oral dexamethason is effective in inducing recovery from an exacerbation of MS.

Antiplatelet therapy in combination with Recombinant t-PA Thrombolysis in Ischemic Stroke.

We hypothesis that antiplatelet therapy adjunctive to rt-PA thrombolysis improves outcome by preventing re-occlusion in terms of three months clinical outcome.

Does treatment with rosiglitazone result in improved pancreatic beta-cell function as compared to glimepiride in metformin treated diabetes type 2 patients?

By inducing a shift of fat out of the visceral compartment - among which the pancreas - into the subcutaneous compartment rosiglitazone results in improved pancreatic beta-cell function in type 2 diabetes patients, as compared to a…

Metabolic effects of Diabecinn (oral cinnamon extract) in diabetes type 2, a placebo-controlled randomized clinical trial.

The main objective of this randomized, placebo-controlled trial is to determine the effects of cinnamon extract on HbA1c and lipid profiles in type 2 diabetic patients.

Efficacy and cost-effectiveness of Short-Term Inpatient Psychotherapy (STIP) as compared to outpatient psychotherapy: a randomized clinical trial among patients with personality disorders in the Netherlands.

It is expected that STIP shows superior efficacy in terms of faster improvement in the first 12 months of the trial and a higher recovery rate at 24 months of follow-up. In addition, it is expected that the higher direct medical costs of STIP are…