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Catheter ablation versus Amiodarone to pRevent Future shock Episodes in patients with a defibrillator and a history of a myocardial infarction.

It is assumed that recurrence of appropriate ICD shocks is 30% in the Amiodarone group and 16% in the Ablation group.

Lipid-induced mitochondrial dysfunction in type 2 diabetes.

Does lipid accumulation in skeletal muscle and the heart effect mitochondrial function in relation to insulin resistance?

Fluoxetine and the developing brain.

Administration of fluoxetine during late brain development (adolescence), but not in adulthood, will result in abnormal outgrowth of the 5-HT system. This long-lasting disturbance of the 5-HT system may be visualized using MRI techniques and can…

Macular Edema following cataract surgery
in Diabetic type 2 patients.

The relative risk of developing macular edema in diabetics after cataract surgery is enhanced.

Minimization of maintenance immunosuppression early after renal transplantation.

Chronic allograft nephropathy is the main cause of long-term renal transplant failure. The pathogenesis involves amongst others calcineurin inhibitors. We performed a multicenter randomized trial to study the effects of withdrawal of ciclosporin (…

TightRope AcromioClavicular Study; TRACS.

Acute Rockwood type 3 AC-luxations will have a better function after operative treatment with the artroscopic TightRope technique than patients treated conservative.

Hypoallergenicity of an extensively hydrolyzed whey protein infant formula in children with cow's milk allergy.

The formula will be tolerated by at least 90% of the children with cow's milk allergy with a confidence interval of 95%.

Effect of a new synbiotic mixture of short chain galacto-oligosaccharides, long chain fructo-oligosaccharides and Bifidobacterium strain on the gut microbiota of caesarean delivered infants.

The study will investigate the effect of a synbiotic test product compared to a control product on the composition and metabolic activity of the gut microbiota of C-section delivered infants.

Lipid-induced insulin resistance.

Administration of a lipid emulsion consisting of long-chain triglycerides (LCT-trial) in non-trained individuals, will induce insulin resistance due to increased DAG accumulation and subsequent activation of the PKC pathway in skeletal muscle.…