581 resultaten
The application of dual site tACS during cognitive training ameliorates spatial neglect symptoms to a larger extent than the application of sham stimulation during cognitive training.
A low ratio of U/DHU and/or T/DHT can cause serious adverse events in patients treated with 5-FU continous infusion.
We expect to see improved white matter integrity (i.e. estimated by increased fractional anisotropy, decreased mean diffusivity) in response to Tecfidera treatment. As a result physical functioning might improve, cognitive functioning will be stable…
The current study aims to investigate the reliability of the AUDIT questionnaire in comparison to the PEth marker value in the general ED population. Thereby we would like to explore if there are advantages of using an objectified direct alcohol…
Intravenous immunoglobulin and intravenous methylprednisolone as optimal induction treatment in CIDP
Primary objective of this randomized controlled trial is to assess whether combining IVIg and methylprednisolone leads to more frequent long-term remission in CIDP compared to treatment with IVIg alone.
We hypothesize that the MBSR-training contributes to reduced stress and absenteeism of teachers in primary education and increased teacher skills, self-compassion, and mental health of teachers.
With data from this study, the following hypotheses will be tested: H1: Youth who nominate a YIM do so based on the relationship and similarities with the YIM. We have no expectations as to why some youth do not nominate a YIM. H2: Youth with fewer…
This pilot study is a feasibility study to verify a shortened scan time duration. We hypothesize that the 30-min protocol provides results as reliable as the 90-min protocol.
6-TG will be a beneficial therapy in about two-thirds of IBD patients whom failed previous therapies, consistent with the literature.
After absorption tamoxifen is metabolized by CYP3A4 and CYP2D6 in several (active) metabolites of which endoxifen is the most important.(11) Tamoxifen, like many anti-cancer drugs, relies on phase II metabolism before they can be excreted from the…
RFID localization for nonpalpable breast lesions is a feasible, non-radioactive alternative for I125-seed localization with regard to the percentage of radical excisions (radical, focally irradical, more than focally irradical) and re-excision rate.
Many hypotheses within the overarching study framework (see summary) related to the main outcomes.
This is an exploratory pilot study without specific hypotheses.
The objective of this study is to evaluate the biomechanical effect of the newly developed rocker soles aiming to reduce the mechanical load in patients suffering with Achilles tendinopathy and plantar fasciitis. A secondary objective is to evaluate…
The research project focuses on identifying early predictors (brain damage, cognition and behavior) for recovery after a SAH. The research also focuses on using advanced neuro-imaging for better mapping of (indicators of) brain damage after a SAH,…
Currently there is little knowledge about the effectiveness of (biopsychosocial) interventions and the cost-effectiveness of adherence to orthopaedic shoes has not been studied at all. Therefore the aim of the current study is to assess the (cost…
This study will address the primary null hypothesis that there is no difference in inter-observer variability for the Geissler classification of SL pathology between surgeons that viewed only radiocarpal and those who viewed radiocarpal and…
VTE risk prediction might be improved by using the modified risk scores.
Three new time-limited psychological (TLP) treatments for anorexia nervosa (AN) will much reduce both treatment duration and costs relative to top-clinical care (TCC).
We hypothesize that muscle protein breakdown (i.e. amino acid release) is related to increased glutamine utilization by immune cells, gluconeogenesis and synthesis of acute phase proteins.