2441 resultaten
1. Comprehensive geriatric assessment has no benefits in selecting patients fit for chemotherapeutic treatment, compared to clinical judgement by the medical oncologist; 2. Observational report of the functional outcome of treating ovarian carcinoma…
The relative risk of developing macular edema in diabetics after cataract surgery is enhanced.
Clients in a consumer-driven program for recovery, empowerment and experiential expertise will have better outcomes on self-efficacy and empowerment than clients on a waiting list for the program.
Immediate PCI in patients with NSTE-ACS is superior to early PCI with respect to 30-day size and occurrence of (non STE) myocardial infarction, death and revascularization.
Chronic allograft nephropathy is the main cause of long-term renal transplant failure. The pathogenesis involves amongst others calcineurin inhibitors. We performed a multicenter randomized trial to study the effects of withdrawal of ciclosporin (…
Because of a high cardiovascular disease (CVD) risk in people with FH, prevention of cardiovascular disease in people with FH is important for health gain and cost reduction. This randomised controlled trial (RCT) focuses on CVD risk reduction…
Treatment with Botox will give a better healing rate for anal fissures compared to treatment with isosorbidedinitrate ointment.
Presence of postural instability and gait dissorder PIGD (gait disorders, balance impairment, falls, fal-related injuries and FOG) are an important and disabling feature of idiopathic Parkinson’s disease (PD) where the level of functional ability is…
1. What are the effects of a minimal intervention given by a nurse and a more intensive psychological intervention on managing fatigue during active treatment of cancer compared to no intervention? Will a minimal intervention be sufficient or is a…
Multiple Endocrine Neoplasia type 1 (MEN1) and Von Hippel-Lindau disease (VHL) are rare autosomal dominantly inherited disorders characterized by the occurrence of various tumors. Therefore, mutation carriers undergo regular screening (yearly for…
rTMS has a positive effect in the treatment of depression.
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Long-chain triglyceride (LCT) emulsions with di-unsaturated fatty acids will lead to enhanced postprandial satiety and reduced energy intake in a subsequent meal, as compared to LCT emulsions with mono-unsaturated or saturated fatty acids.
Compliance with patching therapy for amblyopia can be improved by an educational programme aimed primarily at the child.
1. Parent training will lead to a significant reduction of behavior problems in comparison with routine medical care; 2. Parent training will be as effective as routine medical care with respect to the reduction of ADHD-symptoms; 3. Parent training…
A combined treatment of GH and GnRHa for 3 years in short adolescents with relatively early puberty leads to final height gain.
To determine whether a strategy of invasive treatment (relative to continued medical treatment) of patients with type 2 diabetes mellitus, mild symptoms of stable angina pectoris, and documented myocardial ischemia lead to a decrease in cardiac…
To study the effect of the interaction of cyclooxygenase-2 (COX-2) inhibition (started preoperatively and continued 5 days into the postoperative period) and extended local anaesthetic blockade via paravertebral block on postoperative central…
Non-inferiority (defined as < 12.5% increase) of pooled buffy coat-derived PR platelet concentrates (PR-plasma-PCs) compared to plasma (plasma-PCs) in terms of clinical efficacy determined by WHO grade ≥ 2 bleeding complications.
In line with results from recent pharmacological studies, it is expected that: 1. Inhibiting the cholinergic system by Inversine (Mecamylamine Hydrochloride) results in an impairment of disengagement, but will not affect bias; 2. Inhibiting the…