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Neurocognitive functioning and brain plasticity in high-grade glioma patients: a magnetoencephalography pilot

We hypothesize that a relationship is present between functional connectivity, network features and neurocognitive performance in GBM patients. We also expect treatment and recurrence of the tumor to lead to remodeling of the neuronosynaptic maps…

Differences in glucose production, lipolysis and proteolysis during different basal insulins, in patients with type 2 diabetes.

Differences exist in duration of effect of insulin detemir, insulin glargine or NPH insulin on glucose production, lipolysis and proteolysis in patients with type 2 diabetes mellitus.

A randomized, open-label phase III study of first line chemotherapy in older metastatic breast cancer patients, comparing intravenous pegylated liposomal doxorubicin with oral capecitabine; and the incorporation of a complete geriatric assessment.

This trial aims to demonstrate the superiority of PEG doxorubicin (with 3 months) over capecitabine as first line chemotherapy in patients with metastatic breast cancer.

Bortezomib therapy combined with donor lymphocyte infusion in patients with relapsed Multiple Myeloma following allogeneic stem cell transplantation

The combination of DLI with bortezomib given before and after the DLI improves the Graft versus Myeloma effect without effect on the Graft versus host disease

Which correction protocol gives the lowest cumulative rectal dose in prostate cancer patients who are treated with external beam radiotherapy? A phase II Modelling study

To reduce cumulative radiation dose in the rectum in prostate cancer patients who are treated with curative intent using external beam radiotherapy. We will investigate whether position correction based on implanted gold markers or re-planning based…

Clinical effectiveness and safety of pooled, random donor platelet concentrates, leucoreduced and stored up to seven days either in additive solution with and without pathogen reduction or plasma in hemato-oncological patients.

PAS III-PC and PR-PAS III-PC are non-inferior compared to plasma PC in terms of recovery, estimated by the 1-hour CCI post transfusion

Antibiotic prophylaxis in prevention of urinary tract infections caused by removal of a bladder catheter in children

A short course of amoxicillin/clavulanic acid will not reduce the number of urinary tract infections in children that have been catheterized during a short period.

Intramedullary Nailing of Diaphyseal Humeral Fractures - T2™ Humeral Nail versus Fixion ® Intramedullary Humeral Nail

Theoretically there are many advantages of using the Fixion ® IM Humeral nail, like a significant reduced surgical and fluoroscopic exposure time. The procedure is simple and minimal invasive. No interlocking screws are needed, thus there is a…

Reduction of oxidative stress in COPD by a combination of exercise and nutrition

Daily ingestion of a nutritional supplement enriched with antioxidants during 8 weeks pulmonary rehabilitation results in a decreased oxidative stress in rest and after exercise in COPD patients compared to an iso-caloric placebo.

Amsterdam Spondyloartritis cohort (AmSpA cohort)

Het doel is om een groot overkoepelend cohort te verwezenlijken waarin alle type SpA (zowel non-radiografisch, radiografisch en perifere SpA), alle medicatie type en alle ziekte stadia longitudinaal vervolgd worden en hierbij verschillende ziekte…