391 resultaten
The healing of donor site wounds after split-skin grafting can be promoted by the use of one of five specific wound dressing materials as compared in this trial.
1. The effect of cognitive behavioral therapy in internettherapy and face-to-face therapy is larger then without therapy on women with a sexual dysfuntion; 2. The impact of Internet therapy is just as large as the impact of treatment-as-usual (face-…
Hypothesis: the working mechanims of metformin can be partly explained by its effect on the composition of the gut microbiota, with changes in inretin secretion and inflammatory pathways as secondary effects.
It will be expected that the implementation of the intervention Preventure will reduce alcohol use (binge drinking) by young adolescents (12-16 year).
To assess the current indications for URS and the treatment outcomes in terms of the stone free rate.
The purpose of the study is to conduct a randomised controlled trial with the training course 'Less stress through mindfulness' as an intervention to study the: 1. Effectiveness in terms of reduction of psychological symptoms (depressive…
DYANA Study - Dynamic Annuloplasty System with Activation for the Treatment of Mitral Regurgitation.
To assess the safety and efficacy of the MiCardia Dynamic Annuloplasty System for the treatment of mitral regurgitation with optional intraoperative activation and optimization.
A slow and unpredictable deterioration of the capabilities of the older patient can lead to a vulnerable situation, often unnoticed by the caregiver. As a consequence, care is delayed and acute problems will arise that will need an immediate…
Compared to a ProGrip self-fixing semi-resorbable mesh the use of a Bard® Polysoft™ preperitoneal mesh results in less chronic groin pain in inguinal herniorrhaphy patients.
PHASE 1: 1. Identify the extent to which care management (as a competency) is implemented in the curriculum of postgraduate medical education in the Netherlands; 2. Evaluate stakeholders’ perceptions of the concept of care management (in medical…
Het is veilig en haalbaar om in 1-2 gastroscopieen zowel een BDstent te plaatsen als brachytherapie toe te dienen.
Colesevelam is a bile sequestrant that not only improves lipid parameters, but also improves glycemic control. The workingsmechanismen of colesevelam is yet unknown. We hypothezize that treatment of obese insulin resistant subjects with colesevelam…
It is hypothesised that body weight will decrease and body composition will improve as a result of the intervention resulting from improved lifestyle and energy balance (increase in physical activity and/or lower calorie intake). Musculoskeletal…
In this observational trial we would like to study the possible correlation between the probe-drug dextromethrophan and tamoxifen pharmacokinetics. In case a good correlation is available, this might help in a stepwise development of truly…
Internet-based cognitive behavioural therapy will be more effective than a waiting list for adolescents with chronic pain complaints.
The microcirculatory profile is altered in infants with NEC.
Adalimumab is a more effecient drug than oral claritromycin alone in the treatment of hidradenitis suppurativa.
This pilot study hypothesizes that ICG enhanced near-infrared fluorescence (NIRF) optical imaging enables the intra-operative detection of breast carcinoma in breast cancer patients.
Long-term use of 6-thioguanine is more hepatotoxic, based on histopathological findings, as compared with the long-term use of azathioprine and 6-mercaptopurine in inflammatory bowel disease patients.