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Paravertebral analgesia is associated with superior quality of recovery by achieving comparable pain control whilst having less side-effects.
ARA290 will reduce disease activity in rheumatoid arthritis.
The primary objective is to prospectively identify cardiac damage in childhood cancer patients, during and shortly after treatment with anthracyclines.
We propose that kinase activity profiling may be a potential clinical diagnostic tool to predict for tumor response to targeted therapy with tyrosine kinase inhibitors (TKI's).
The hypothesis is that twins discordant for pregnancy complications display a distinct epigenetic signature in MSCs. This signature contributes to cellular metabolic alterations and is associated with future cardiovascular and neurodevelopmental…
Not applicable
The goal of the proposed study is to test the null hypothesis that vaccination will not boost the cytotoxic T cell responses against UTA2-1 in >20% of the patients.
The pharmacotherapeutic treatment of patients with cancer is generally associated with multiple side-effects. The cause of the side-effects is usually due to the toxicity of the drugs themselves. In addition, drug interactions can intensify side-…
This project aims to investigate the feasibility and oncological safety of eFTR as minimal invasive completion treatment following previous incomplete endoscopic resection of low-risk T1 CRC.
The hypothesis to be tested is that arm B is tolerable and that the outcome in arm B is better than in arm A.
Chronic chilblains is a common disease causing major restrictions in daily life, nevertheless little is known about treatment. In a literature search, we found thin evidence of three interventions: fluocinolone cream, nifedipine and vitamin D3.…
Combining digital FDG-PET/CT and DW-MRI imaging will more accurately predict and define response in rectal cancer patients after neoadjuvant treatment.
Very limited treatment options are available with a rapid onset to counter off periods in Parkinson’s disease patients. Therefore, the development of rapid onset levodopa formulations is warranted, for which an inhalable formulation of levodopa is…
In terms of effectiveness, we hypothesized that for each patient during treatment: 1 Compared to a waiting list baseline, the intensive inpatient treatment with adapted ST interventions together with ST milieu therapy during 12 weeks results in…
There are significant differences in the quantitative data for the groups of normally sigthed and visually impaired children older than 6 years. The hypothese is that is also for children from 2 until 6 years.
The pharmacokinetics of erlotinib 150mg QD is comparable to the pharmacokinetics erlotinib 75mg + ritonavir 200mg QD.
Based on recent data derived from animal research in combination with earlier clinical trials, we hypothesize that stimulation of cerebellar nuclei in pediatric refractory epilepsy patients might be effective in significantly decreasing epileptic…
1. Post-migration stressors are associated with parental self-efficacy controlling for war-trauma 2. Parents feel more efficacious on days with less post-migration stressors and vice-versa 3. Real Tailored Verbal feedback on parenting will improve…
Current frailty screening practice can be improved in specialized burn care
We expect (in the intervention condition as opposed to the control condition): 1. A decrease in children's emotional/behavioral problems and rule-braking behavior; 2. An increase in children's on-task behavior; 3. An increased teacher…