342 resultaten
To determine whether a second IVIg course in GBS patients with a poor prognosis improves functional outcome after 4 weeks. Secondary outcomes include functional outcome after 8, 12 and 26 weeks, mechanical ventilation, length of hospital and ICU…
Our hypothesis is that the iron status in young healthy children from the Netherlands might be insufficient.
1. Intensive Outpatient Mentalisation-Based Treatment (IOP-MBT) and Day Hospital Mentalisation-Based Treatment (DH-MBT) will both result in clinical improvement for patients with severe Personality Disorders (PDs); 2. Matching-hypothesis: the…
The objective of this study is to assess which Patient Reported Outcomes are used in follow-up studies of Charnley’s Hip Replacement Arthroplasty and to assess the prevalence of reporting Patient Reporting Outcomes in time.
BB3 will improve kidney function in the immediate post-transplant period in patients who have received a DCD kidney transplantation.
Several new imaging techniques have been developed in order to improve differentiation of colonic lesions, one of these is confocal endomicroscopy. The objective of the proposed study is to evaluate the feasibility and additional value of confocal…
To assess the tolerability and efficacy of the addition of oral tosedostat to standard induction therapy.
Feedback to the COPD patient about his condition and physical activity plays an important role in promoting self management. Within the current care for patients with COPD, there is a lack of insight into daily activities and lack of understanding…
The hypothesis to be tested is that by consequent screening and subsequent treatment with optimized treatment strategies of patients with advanced cancer the quality of life and their communication with family can be improved. In addition, we…
Helium inhalation influences the coronary circulation and/or vessel diameter.
An ICT-supported, integrated, multidisciplinary treatment of COPD in primary care compared to usual care in primary care practices will improve the quality of life of COPD patients at an acceptable level of cost-effectiveness.
Genestein inhibits the synthesis of heparan sulphate and can possibly slow down disease progression in Sanfilippo Syndrome patients.
To gain more insight into the pathogenetic processes involved in Sjogrens Syndrome(SS) bij analyzing the infiltrate and structural changes in salivary glands of SS patients and compare these findings to those in other (aspecific) inflammatory and…
Giving smokers (who are motivated to quit smoking) an attentional retraining to train away the attention they have for smoking related stimuli will be significantly more effective in preventing smoking relapse than giving them a non-training version…
Intra-operatieve fluorescente beeldvorming van schildwachtklieren bij baarmoederhalskankerpatienten.
Fluorescent near-infrared imaging can accurately detect sentinel lymph nodes non-invasively during lymphadenectomy in cervical cancer patients.
We therefore hypothesize that FABP/Claudin levels may be used as a diagnostic tool for the identification of intra-abdominal injury necessitating surgery and as a prognostic marker for the development of SIRS/MOF (and morbidity and mortality) in…
Pelvic floor related symptom and Quality of Life questionnaires (IIQ-7, UDI-6, IIEF-5, PISQ-12, PFIQ-7, PFDI-20, FISI, FIQL) in Dutch are valid instruments, which can be used reliably in daily practice and clinical research.
The aim of this project is to determine optimal communication strategies for prognostic disclosure in the palliative phase of breast cancer from a patient perspective. Study 1: To explore breast cancer survivors’, healthy women’s and oncologists’…
There is clear medical need in pediatric high-grade MDS and JMML to control disease pre-SCT without the disadvantages associated with intensive chemotherapy. So far no agents have been successfully applied in this window, or are specifically…
1. The point of the skin with best possible transcutaneous nerve stimulation correlates with the point of the skin most superficial to the nerves stimulated within a range of 3 mm; 2. Ultrasound will reveal a significant number of sensitive…