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RAR-CLA and cognition

Daily supplementation of 3.5g RAR-CLA will slow down cognitive decline as compared to placebo

Safety, tolerability, pharmacokinetic (PK) and pharmacodynamic (PD) study with ENX-201

A relationship exists between a pharmacologic effect of ENX-201 and the plasma concentration

A randomized controlled trial on the effect of pre-thickened oral nutritional supplements on nutritional status of nursing home residents with dysphagia and (at risk of) malnutrition

Daily use of pre-thickened oral nutritional supplements for 12 weeks will have a positive effect on body weight of older nursing home residents with dysphagia and malnutrition (risk) as compared to standard nutritional - and dysphagia management

Reducing primary and secondary cesarean delivery rates in women with a previous cesarean delivery using electrohysterography: randomized controlled trial

We hypothesize that the percentage of successful TOL will increase with the use of EHG because EHG provides more accurate assessment of UA, allowing for better optimization of the contraction pattern during labor. Besides, more reliable monitoring…

Clinical study to evaluate the safety and efficacy of recMAGE-A3 in patients from which the bladder is removed due to muscle invasive bladder cancer.

The disease free survival will be prolonged in MAGE-A3 positive patients treated with recMAGE-A3.

Nierdenervatie als behandeling van hoge bloeddruk na niertransplantatie.

We hypothesize that catheter based selective renal denervation of the native kidneys in renal transplant recipients will improve blood pressure control and diminish the number of antihypertensive drugs.

Biomarkers van chronische ontstekingsziekten van de gewrichten.

The goal of this study is to identify and validate recently discovered and novel biomarkers of pathophysiology, diagnosis, classification, disease activity, prognosis, treatment susceptibility, and treatment efficacy in chronic inflammatory…

A phase II study of ARA 290 as therapeutic strategy in no-option critical limb ischemia patients.

The objective of this proof-of-concept study is to test in no-option CLI patients whether ARA 290 (a) reduces limb pain, (b) reduces signs of local and systemic inflammation, and (c) promotes wound healing.

Triptorelin Oral contraceptive Pill Flare-up in IVF/ICSI Treatment trial.

The aim of the study is to show non-inferiority of a short, flare-up GnRH-agonist protocol to the GnRH-antagonist protocol, both with OC pill pre-treatment, in women undergoing in vitro fertilisation (IVF) or intracellular sperm injection (ICSI)…

Catheter ablation versus Amiodarone to pRevent Future ventricular tachycardia Episodes in patients with a defibrillator and a history of a myocardial infarction.

Time to recurrence of sustained VT (longer that 30 seconds or with hemodynamic instability) or VF with or without documented ICD therapy (shock or ATP) for VT of VF will be longer in patients randomized to substrate based ablation than in patients…

An exploratory study to evaluate the effect of a new study product on early programming in healthy infants.

The investigational formula will be equivalent to the control formula with regard to the postprandial blood lipid parameters.

Comparison of Volulyte® versus Tetraspan® in patients undergoing cardiopulmonary bypass.

Does the use of two different balanced hydroxyethyl starch solutions, influence the coagulation profile, acid-base status, ionogram, colloid oncotic pressure and organ function in patients undergoing cardiopulmonary bypass.

Nebulising Amoxicillin-Clavulanic Acid in Patients with COPD.

Nebulizing amoxicillin clavulanic acid is more effective for reaching amoxicillin levels in sputum > MIC90 than amoxicillin clavulanic acid given by oral or intravenous administration.

Effecten van Neuromusculaire Electrostimulatie (NMES) op fysiek functioneren en skeletspiermassa bij acuut zieke geriatrische patiënten met sarcopenie opgenomen op de afdeling geriatrie van ZMC

Beoordelen van de effecten van NMES op fysiek functioneren en spiermassa.

Het Effect van Renine-Angiotensine-Systeem Inhibitie op Progressie van Aortadilatatie bij Patiënten met Coarctatie van de Aorta.

Het primaire doel van de studie is om de effecten van RAS-inhibitie op de progressie van dilatatie van de aorta ascendens te bestuderen met cardiac magnetic resonance imaging (CMR) bij CoA patiënten, en dit te vergelijken met CoA patiënten zonder…

Stoppen van medicatie bij jarenlang stabiele MS: een gerandomiseerd gecontroleerd onderzoek.

Deze studie zal onderzoeken of het veilig is om immunomodulerende therapie te staken bij patiënten met multiple sclerose die de afgelopen vijf jaar geen tekenen van inflammatoire ziekteactiviteit hebben vertoond.Primaire onderzoeksvraag:- Kan…