581 resultaten
We hypothesize that PHA-022121 will be more effective in both the treatment and prophylaxis of acute angioedema attacks in patients with acquired C1-inhibitor deficiency when compared to placebo.
Background: Injury rate and injury severity of elderly cyclists due to self-induced cycle accidents increase with age. Starting at the age of 55 years, injury risk increases with a factor 4 at the age of 75 years. Injury mechanisms such as slippery…
In patients with ANOCA, identification of specific endotypes of vascular dysfunction with intracoronary testing, followed by pharmacological and nonpharmacological interventions aligned to the identified endotype, leads to better control of angina…
The combination of breast surgery, radiotherapy and chemotherapy have a profound effect on the deep myofascial level and in turn, they create a vicious circle of adhesions and lack of mobility and pain in muscles, fasciae and joints around the…
Combination therapy with telaprevir/ ribavirin is as effective as the current standard of care with peginterferon-alfa/ ribavirin for the treatment of acute Hepatitis C in HIV-infected individuals.
Not applicable
We hypothesize more than 90% of the participants in the in-hospital, standard-of-care follow-up will contact the hospital during the study period and 40-50% of the patients in the patient-led, home-based follow-up will contact the hospital between…
Our hypothesis is that custom made insoles and a home-based exercise program would be superior to a home-based exercise program alone at 12 weeks follow-up.
The school-based sleep intervention is effective in improving self-reported sleep quality.
In adult congenital heart disease patients with exercise-induced pulmonary arterial hypertension, treatment with bosentan lowers the mean pulmonary arterial pressure, which may result in improvement of the cardiopulmonary circulation,…
Regarding our main objectives, we hypothesize that patients with a gambling disorder show an increase in dopamine synthesis capacity. Moreover, we hypothesize a positive relationship between individual differences in dopamine synthesis capacity and…
We expect to find that e-liquids with nicotine salts taste milder and are easier to inhale than e-liquids with free-base nicotine. More specifically, we hypothesize that e-liquids with nicotine salts, in comparison to free-base e-liquids: 1. are…
The effectiveness of school-based ('Op Volle Kracht') and computerized ('SPARX') depression prevention programs will be tested in a Dutch sample of adolescent girls with elevated depressive symptoms. The programs will be tested…
Is a prevention program, based on principles of health behavior change, education about playing-related musculoskeletal disorders and postural training, more effective in preventing and/ or reducing disabilities from musculoskeletal complaints in…
The hypothesis of the TRANSFORM II study is the non-inferiority of Sirolimus Coated Balloon versus Everolimus Eluting Stent in terms of Target Lesion Failure
3D printed tailormade assistive aids may better fulfill the requirements and needs of clients with disabilities to support them in performing their activities of daily living than the currently available aids or handmade aids provided by…
Organoids can be cultured from pancreatic ductal biopsies, obtained from chronic pancreatitis patients, to study electrolyte and fluid secretion.
The hypothesis is, when adolescents are screened for problems at an early stage and do get help, they will be less absent from school and will have less psychosocial problems.
Participant demographics affect the health state. TPO-RA treatment affects the severity of symptoms, overall health condition, health state, overall satisfaction with therapy and reasons for discontinuation. TPO-RA treatment affects direct…
COMET measurements are feasible in patients with PAOD and the measurements are tolerable.