2887 resultaten
Primary Objective: Establishing the course of surgical fear, assessed by the surgical fear questionnaire at multiple time points, from one week before surgery until the day of surgery. Secondary Objectives: • Establishing the convergent validity of…
Allogeneic blood transfusions are reduced when comparing the use of an ABT system to no use of post-operative drains in patients who underwent TKA.
H0: The effect of using test intervention is equal to the effect of the control intervention with respect to change in leg muscle mass in obese older adult patients with type 2 Diabetes after 13 weeks of intervention H1: The effect of using test…
• CT based Signature™ will result in a comparable percentage of prosthesis that is placed correctly (within guidelines of 3 degrees varus and 3 degrees valgus). • CT-based Signature™ will result in a comparable alignment of the prosthesis as…
1) Tapering of SSRIs with added preventive cognitive therapy (CT) increases the risk of clinically relevant maternal relapse of depression in excess of [absolute] 15% compared to continuation of SSRIs. If rejected, then discontinuation is deemed non…
The overall aim of this study is to study the effectiveness of a PLISSIT-model intervention in men and women with type 2 diabetes in primary care. Primary outcomes include sexual functioning, sexual satisfaction, and quality of life. Secondary…
The central hypothesis is that the mobile programme is more effective than the web-based programme in increasing physical activity (PA). i.e. 1. Both intervention groups will show an increased PA level. 2. Participants of the mobile programme…
This study has 2 primary objectives: 1) To determine the time point of induction of VEGF expression in the tumour tissue of oesophagus carcinomas during chemoradiation. 2) To determine whether the tumour promoting effects of this induction of VEGF…
To investigate whether patients prefer to be approached by mailed questionnaires for annual follow-up assessment after PCI procedures versus telephone interviews or email-based follow-up
The primary objective is to estimate the frequency of subjects with at least one apnoeic episode, defined as respiratory rate ≤6, detected using the respiR8® device for up to 6 hours after surgery. Apnoea is defined as 10 seconds of no breathing…
We hypothesize that age-related changes in hepatic and intestinal drug metabolism affect the pharmacokinetics of paracetamol.
- The incidence of PONV will be higher in the group receiving dexamethasone alone - There will be no significant difference in the incidence of PONV between the two groups receiving two anti-emetic drugs - There will be less postoperative agitation…
The use of a decision support system will increase adherence to the ESC guideline for atrial fibrillation in terms of calculation of bleeding and stroke risk, and accurate anti-thrombotic treatment for stroke prevention.
We hypothesize that adaptation or tuning of the population PKPD model of propofol will decrease the residual error between predicted and measured plasma-concentrations during maintenance of anaesthesia. The adapted PKPD models can also be used…
Low-molecular-weight heparins (LMWHs) are frequently used in the prophylaxis and therapy of venous thromboembolism (VTE) and the prophylaxis of arterial thromboembolism. LMWHs are mainly excreted by the kidneys and may accumulate in patients with…
With a multi-faceted strategy we are able to implement shared decision making so that it meets the needs and demands of both professionals and patients, without interfering in daily practice.
The aim of the pilot trial is to: 1. evaluate the potential effectiveness and effect size of the e-support program for parents of children with a chronic kidney disease; 2. to identify outcome measures most likely to capture potential patient…
Pulmonary rehabilitation prior to bariatric surgery is effective by means of outcome (asthma control, complications, recovery, physical condition, quality of life) after the bariatric surgery.
We expect that when the developed checklist will be used in de diagnostic proces of children with developmental and/or behavioral disability, the use of pediatric care will be more efficiently used. Over and underdiagnoses of a causal somatic…