3342 resultaten
Vitamin D plays an integral role in calcium and phosphorus homeostasis. A low vitamin D status can occur as a result of reduced synthesis due to lack of sun exposure, decreased intake or absorption, increased hepatic catabolism, or decreased…
Sunitinib, when given in a high-dose, intermittent schedule, may exhibit improved efficacy in patients with recurrent GBM with an acceptable toxicity profile, compared to lomustine.
Implementation of Syncope Algorithms (SAs) in the Netherlands will increase diagnostic yield, avoid unnecessary admissions and improve quality of life (QoL) by offering timely diagnosis & treatment
We hypothesize that, asymptomatic patients with severe aortic stenosis, receiving an aortic valve replacement have a better quality of life compared to patients without aortic valve replacement.
Our hypothesis is that our gradually progressive protocol offers advantages with respect to the eccentric protocol based on the protocol of Alfredson (gold standard). We expect that, because this protocol is more individualized, less pain during the…
The primary aim of the study is to investigate patient characteristics that predict (differential) treatment response across MBT and ST. In addition, mechanisms of change in MBT and ST will be examined. Furthermore, the (cost-)effectiveness of MBT…
The hypothesis is that all procedures look different per therapist and parent collaboration and all experiences are different. Nevertheless, there possibly will be similarities in experiences and wishes for the future.
We expect to develop a robust predictive model with which to identify patients who are most likely to benefit from STN-DBS, thereby optimizing the screening procedure for DBS.
single denosumab injection has a beneficial effect on shortening time in contact cast and foot form preservation in DM subjects with an acute charcot foot
Participants in the intervention group will show a larger decline in household chaos than participants in the control group. As a result parenting quality in the intervention group will improve more than in the control group. Secondary hypotheses…
A. COMET as an additional transdiagnostic intervention focusing specifically on low self-esteem increases the effectiveness of mentalization based treatment in patients diagnosed with borderline personality disorder. B. This increased effectiveness…
"De Nieuwe Toekomst" will empower female victims of intimate partner violence by making them financial independent which reduces the risk of intimate partner violence victimisation
To determine the influence of optical quality on perimetry for phakic and pseudophakic healthy and glaucoma patients. To determine the influence of CLE on perimetry and optical quality for PAC patients.
Our null hypothesis is that there are no differences in tibiofemoral joint kinematics after ACL reconstruction with LET and the tibiofemoral joint kinematics after ACL reconstruction without LET. Our alternative hypothesis is that ACL reconstruction…
Cranberry capsules given peri-operatively reduce the risk of clinical overt urinary tract infection after elective pelvic floor surgery with indwelling catheter postoperatively compared with placebo
We hypothesize that 1) fasting duration may affect the central serotonin and dopamine systems, either centrally or indirectly through effects on peripheral input to the central nervous system, and 2) the effect of fasting may be changed in obesity.
The aims of the study are: To investigate the short-term effectiveness of antecedent and consequent behavioral parent training techniques for parents of children (four to twelve years old) with attention-deficit/hyperactivity disorder (ADHD) on…
Survivors of sepsis are at high risk for the development of chronic kidney disease (CKD), cardiovascular events and mortality. Mitochondrial dysfunction, which mainly results from increased generation of free radicals, plays a key role in the…
The aim of this study is to show whether TDM leads to a lower proportion of patients with drug levels below the predefined TDM targets after 12 weeks
With implementation of the AWR and APWR by the ED triage nurse we expect a reduction in the total number of radiographs requested, without missing any clinical relevant fractures. We also expect a reduction in overall waiting times at the ED and…