4200 resultaten
Hyperthermic intraperitoneal chemotherapy (HIPEC) has become standard of care for patients with peritoneal carcinomatosis of colorectal origin with a low/moderate abdominal disease load. In case of a peritoneal cancer index (PCI) above 20, a HIPEC-…
To study if a Mediterranean diet (MD) followed by lean donor fecal microbiota transplantation (FMT) has synergistic superior beneficial effects on peripheral insulin sensitivity and (small) intestinal microbiota composition as compared to…
We hypothesize that a semi-rigid ankle brace especially designed for soccer players, wil reduce the incidence of ankle sprain injuries among amateur girls soccer players by 50%.
Electroconvulsive therapy (ECT) is the most effective treatment for severe depressions. Unfortunately, several cognitive side effects with a large pallet of different manifestations and impact often occur. For instance, postictal agitation ((PIA)…
We hypothesize that the subjective well-being of individual patients will show improvement after dose reduction compared with baseline, that is, patients will experience more positive affect, less negative affect and higher physical well-being…
Early identification of and specific interventions for older ED patients at highest risk of various poor outcomes contribute to the prevention of adverse events and lead to more efficient ED care.
Inguinal hernia repair according to the TREPP technique results in less patients with chronic postoperative inguinal pain (CPIP) compared to Lichtenstein's technique.
To investigate whether myocardial blood volume (MBV) is reduced in patients with non-obstructive coronary artery disease and signs and symptoms of ischemia, relative to healthy controls. The specific aims are to investigate 1) if MBV is reduced in…
Traditionally, all surgically removed appendices and gallbladders are sent to the department of pathology for histopathological examination. This is most likely not necessary in appendices and gallbladders that are not suspicious for a malignancy…
To determine the presence or absence of central sensitisation in patients with Chronic Low Back Pain with radiation to the leg (CLBPr) and to determine the effect of segmental nerve interventions on central sensitisation.
We hypothesize to attain a drop of 20% of completed suicides in Noord-Brabant, the Netherlands.
The main objective of this study is to investigate which communicative strategies are most effective in increasing understanding and decreasing emotional impact in communicating increased risk for developing dementia status to persons with mild…
The primary hypothesis is that playing the serious game 'You & I' will be associated with an improvement of the mentalizing abilities in adults with mild to borderline intellectual disabilities. The secondary hypothesis is that…
We hypothesize that cardiovascular disease and impaired quality of life are frequent long-term complications in AAV and often underdiagnosed.
Poor glycaemic control, indicated by an elevated HbA1c, is correlated to poor postoperative outcome in patients with diabetes mellitus undergoing surgery. However, improving glycaemic control before surgery has not been extensively studied so far.…
a. Ascorbic acid in combination with metformin (500mg BD) improve the glucose tolerance with a daily dose of 500mg over a period of 12 months. b. Ascorbic acid with metformin reduce the adverse effects/events. c. Acetylesalicylic acid in…
If there is a correlation between liking by smelling and liking by vaping, future experiments on e-liquid flavors would require smelling experiments only.
• To evaluate the safety and tolerability of three oral dose levels of LTI-291 following 28 days of LTI-291 treatment in patients with Parkinson’s Disease with GBA-PD. • To characterize the plasma and CSF pharmacokinetics (PK) of LTI-291 following…
In primary prostate cancer patients, the exisstence of lymph node metastases is associated with developmment of distant metastases and negatively associated with cancer-specific survival. The performance of an extended lymph node dissection (ePLND…
The Victoria modules are thought to have a positive effect on acknowlegdement for adversities and risk awareness. This can be used to take acceptable risks in rehabilitation process. This will then lead to more societal participation and less…