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We hypothesize that, asymptomatic patients with severe aortic stenosis, receiving an aortic valve replacement have a better quality of life compared to patients without aortic valve replacement.
Our hypothesis is that our gradually progressive protocol offers advantages with respect to the eccentric protocol based on the protocol of Alfredson (gold standard). We expect that, because this protocol is more individualized, less pain during the…
The goals of this study are to evaluate the initial performance, safety and functional results of the Anser; A novel intramedullary device for fixation of midshaft clavicle fractures.
We predict that matching user needs and characteristics with feedback properties increases chances of sustained use of the intervention, as well as eating behaviour change. Furthermore, greater social sharing of platform results (both on- and…
Fatigue in patients with primary Sjögren's syndrome can be explained by force decline during a fatiguing task, muscle activation, mood, and the serum levels of proinflammatory cytokines. Patients with primary Sjögren's syndrome will show…
Because of the impact of chronic abdominal pain in children and the long term prognosis with impressive consequences for the life of the patients and for the society, it is important to aim at optimal therapy. Standard therapy is rather ineffective…
Implementation of standardized multi component intervention package tailored to ICU patients which focusses on reducing modifiable delirium risk factors by nursing and physical therapy interventions
The aim of this study is to describe the last phase of life of people with young-onset dementia. The research questions for this prospective observational study are: 1. What is the practice of end of life care in people with young-onset dementia…
We hypothesize that cardiovascular disease and impaired quality of life are frequent long-term complications in AAV and often underdiagnosed.
In this study we explore the feasibility of combined decitabine and cytarabine chemotherapy in AML and high risk MDS patients with a high risk of early mortality (day 30 mortality) during standard induction chemotherapy (HCT-CI co-morbidity index…
Studies on PSMA PET/CT the past few years are promising but often of retrospective nature and with heterogeneous patient populations. In our academic centre there are currently two trials running with 18 F-FDHT PET/CT. Results are promising, but…
Aim of the study is to determine the neuronal correlates of post-stroke epilepsy and cognitive dysfunction, in PSE and non-PSE stroke patients, and healthy controls.
Competitive Memory Training (COMET) will improve self-esteem, anxiety symptoms, depressive symptoms and behavior problems in youth with ASD.
Psychoeducation is recommended after diagnosis. For older adults with autism there currently is no evidence based psychoeducation available. We hypothesize that participating in our psychoeducation will lead to a more comprehensive understanding of…
Implementation of the Namaste Care Family program will improve lives of Dutch nursing home residents with advanced dementia and their families
Environmental disturbances during ICU submission may explain observed EEG-arousals
Is an intensive multimodel multicomponent program for caregivers of people with dementia more effective than care as usual on the well being of the carer and the person with dementia.
The purpose of this observational study is to obtain insight into the treatment of the acute phase of Crohn’s disease with Budenofalk® 9 mg granules and 3 mg capsules among outpatients attending regular gastroenterological practice. Likely,…
The primary aim of this study is to evaluate NET in SMI patients with comorbid PTSD associated with repeated interpersonal trauma whether: a) the PTSD symptoms changes and b) changes occur in the present SMI symptoms, care needs, quality of life,…