3043 resultaten
The primary aim of the current research project is to establish whether the current Dutch vision screening in children aged 3-6 years old in PYHC can be improved by using plusoptiX, with regard to costs and screening performance.
In the Netherlands, family members at risk of inherited cardiac disease are generally informed by the index patient (i.e., the first in the family diagnosed with an inherited cardiac disease) about the advice of cardiac monitoring and predictive…
We hypothesize that dietary nitrate supplementation improves muscle strength and muscle endurance performance.
The primary objective of the study is to examine whether the WhiteTeeth app used by orthodontic patients aged 12 to 16 improves oral health behavior and oral hygiene. Primary outcomes of this RCT are dental plaque levels, gingival bleeding upon…
This study aims to provide a compendium of reference values of absolute aerobic loads of daily activities for people after stroke. Additionally, it will provide insight in the importance of aerobic fitness for daily living. Our study results will…
Current treatment of patients with symptomatic chronic pancreatitis (CP) and obstructive main pancreatic duct stones consists of extracorporeal shockwave lithotripsy (ESWL) followed by endoscopic retrograde pancreatography (ERP) to extract the…
The study will assess drug-induced change in performance in divergent thinking and goal-directed behaviour when comparing psilocybin to placebo, before and after an induction of stress. Additional study parameters include frontal-subcortical…
A goal directed nutritional support can reduce sarcopenia in surgical esophagus patients.
The TOF Cuff NMT monitor is as reliable as the TOF-Watch SX acceleromyograph for perioperative neuromuscular monitoring.
The overall 1- and 5-year survival rates after liver transplantation are nowadays well established at approximately 90% and 70%, respectively. Unfortunately, long-term patient survival rates after OLT lag behind, with an overall 20-year survival…
To determine the level of nilotinib detectable in seminal fluid of men treated with this tyrosine kinase inhibitor And to form an advise if condoms are necessary to protect their sexual partners from exposure to nilotinib.
High-dose single-fraction radiotherapy (SBRT) to the primary lung tumor combined with dual immune checkpoint inhibition is safe and feasible and will increase both the systemic response rate to these agents and induce more durable tumor responses…
This phase 0 study will serve to understand the variation in potential pharmacodynamics biomarkers (and methods of analyzing these biomarkers) to be implemented in planned first-in-human single and multiple ascending dose studies with a novel GCase…
Blood pressure status affects the perfusion of the optic nerve head and the retina in subjects with vascular or autonomic dysregulation. Optical Coherence Tomography Angiography is capable of showing the effect.
We expect the number of seizures to decrease with the introduction of a seizure dog. Besides the effect of seizure dogs on seizure frequency, we expect an impact on participation, well-being, health-related quality of life, healthcare resource use (…
True NC-FET is non-inferior to modified NC-FET in ongoing pregnancy rate after one FET cycle.