507 resultaten
DBS-related cognitive decline and psychiatric side-effects in Parkinson's disease (PD) patients can be studied from a functional- and structural network point of view. We will characterize functional and structural brain networks in PD patients…
The primary objective of the study is to investigate the role of expectations on conditioned pain modulation (CPM). Based on previous research it is expected that negative outcome expectations, induced by the verbal suggestion that a second painful…
Preventive parenting support for parents after separation, leads to: - more knowledge about (co-)parenting strategies; - more intentions to use positive (co-)parenting strategies; - increased feelings of competence; - increased awareness on the…
Training for the HandbikeBattle and handbike training in general, will have a positive effect on physical health, physical fitness and quality of life in wheelchair dependent individuals.
Primary Objective: To gain insight in the disease mechanisms of IBD. Secondary Objective(s): To identify biomarkers and study functional and mechanistic properties of the mucosal immune system, gut and oral microbiome, epithelium, mucus barrier,…
1. The augmentation in scores (t2-t1 and t3-t1) is higher for EYT group than control group on the original complaint controlled for other treatment. 2. The augmentation in scores is higher for EYT group than control group on self-determination. 3…
In this randomised, double-blind, placebo-controlled single centre study we propose to study the effect of duodenal infusion of single E. hallii treatment (administered via duodenal tube) on small intestinal gene expression, bacterial composition…
A limited endoscopoic assisted laparoscopic wedge resection of colon polyps is safe and effective.
Patients's satisfaction will be good independable of the time interval between follow-up and meniscal allograft transplantation (MAT). Patient Reported Outcome Measures (PROMs) will be significantly higher postoperative compared to preoperative…
Bone-anchored maxillary protraction therapy improves facial profile in cleft children.
The Rotterdam Study studies causes of diseases in the elderly, as a response to demographic changes leading to an increase of the proportion of elderly people in most populations.
Hypothesis 1: Participants in both conditions (experimental and placebo) will show a reduction in gamble problem severity immediately post-intervention and at 3-and 6-month follow-ups. However, participants in the experimental condition will show a…
To evaluate the anti-inflammatory effects of 3 months statin therapy on vessel wall inflammation by means of FDG PET/CT in patients with CKD.
An early mobilization program in critically ill children reduce the consumption of sedatives and opioids and the prevalence of delirium.
We hypothesize that the range of motion of the hallux is limited during gait in patients with hallux rigidus (HR). In addition, we hypothesize that patients with HR will compensate this loss of motion of the hallux by increasing joint motion in the…
Combining factors will enable prediction of successful long-term video-EEG monitoring and of adverse effects, related to antiepileptic drug withdrawal.
Acid-reducing drugs, such as PPIs, may profoundly decrease solubility and, as a result, (negatively) affect the bioavailability of afatinib. Since a PPI is often used concomitantly during afatinib therapy, this DDI confronts physicians, patients,…
- brain activation and connectivity during emotion regulation, thinking about future events, inferring on emotions of others and rest are different in patients with a recent suicide attempt compared to patient controls and healthy controls - brain…