577 resultaten
We hypothesize that the amino acid loss in the dialysate during a routine HD session in the MUMC+ will be between 8-12 g/session, resulting in a significant decline in plasma free amino acid concentration.
The primary hypothesis is that preconscious attention bias modification (ABM) training towards and away from pictorial itch stimuli results in altered preconscious attention for pictorial itch stimuli. Secondarily, it will be explored whether…
Theoretically, central sensitization can be plausible linked to pain intensity and to physical functioning. Some evidence is found for the relation between sensitisation and intensity of pain, but not with physical functioning.
Measuring patient reported experiences in the Dutch disability sector is not performed integrated leading to measuring redundance and lack of motivation from both the client as well as the care professional to perform the measurements. Het meten van…
First, to develop a 4D computer-assisted diagnostic method for estimating the cause of posttraumatic impairment of the forearm. This method is intended to allow differentiation of motion patterns reflecting mutual impingement of radius and ulna from…
We hypothesize that the occurrence of severe post partum hemorrhage will approache the incidence in the normal population after implementation of a revised national guideline on the management of pregnancy in women with VWD or hemophilia carriers
PVAT plays an important role in driving vascular ageing manifested by medial smooth muscle cell (SMC) dedifferentiation into an osteogenic phenotype that induces intimal and/or medial calcification. I furthermore hypothesize that this process of…
IPA as first-line therapy in the Emergency Department leads to: - faster initiation of symptomatic treatment for nauseous patients - more patients receiving symptomatic treatment for nausea - a decrease in the use of conventional anti-emetics - a…
Two-stage implant-based breast reconstruction is the most common reconstructive technique after mastectomy. It is associated with some implant specific complications such as capsular contracture. Capsular contracture is one of the most frequent long…
Aim of the MANCO study is to establish for once and for all that monitoring the effect of heparin during NCVI is essential to ensure the individual patient of safe and tailor-made anticoagulation. Not measuring the effect of the administered heparin…
It is hopthesized that a multidimensional implementation approach with multiple interventions integrated in the usual care will improve physical behaviour during hospitalization
To test the safety and preliminary efficacy of a dual acute thrombolytic treatment consisting of a small intravenous (IV) bolus of alteplase followed by IV infusion of HisproUK against usual treatment with IV alteplase in patients presenting with…
In primary prostate cancer patients, the exisstence of lymph node metastases is associated with developmment of distant metastases and negatively associated with cancer-specific survival. The performance of an extended lymph node dissection (ePLND…
Addition of Partner for Change Outcome Management System (PCOMS) to individual treatment will result in a significant decrease of drop-out compared to individual treatment without PCOMS in a forensic outpatient clinic in the Netherlands. A sub-…
The development of a computer aided detection (CAD) system might be able to assist endoscopists in the recognition and subsequent characterization of early Barrett's neoplasia, thereby improving efficacy of BE surveillance.
To determine the safety and tolerability and to assess the PK and performance of VB5-845D-800CW in healthy volunteers and patients
To compare patient reported health-related quality of life outcomes (PROs) between BRCA 1 or 2 gene mutation carries who choose breast surveillance or bilateral prophylactic mastectomy with immediate reconstruction.
The prevelance of FGID in patients with uncomplicated gallstones is higher compared to the general population
We hypothesize that treatment with pelvic physiotherapy in patients with a chronic anal fissure and concomitant pelvic floor dysfunction will result in an improvement of quality of life. We also aim to provide a management protocol for Pelvic floor…