2939 resultaten
Adalimumab dose reduction based on serum drug concentration will not affect clinical efficacy of adalimumab, while it will minimize medical costs.
We hypothesize that adolescents who play a serious game as add on to the regular CBT stay more interested to play the game, are satisfied with the game, do more homework and are able to apply the learned strategies in real-life. We expect little…
Atherosclerosis is a chronic inflammatory disease of the artery wall. Treatment of atherosclerosis has been based on lipid lowering therapies for years, reducing multiple risk factors. Adaptive immunity plays a key role in the pathogenesis of…
Manipulation of the flocculus and presence of a cerebellopontine angle tumor comprises the functions of the flocculus, leading to tinnitus. Moreover, inflammation in the cerebellopontine angle and particularly of the flocculus leads to altered…
application of IBT in a GP practice is effective for the treatment of sexual problems
H0: Implementation of a systematic and targeted screening of fall risk among independently living frail older people in primary care will not influence on the number of referrals to existing evidence-based fall prevention interventions. H1:…
test-retest repeatability of radiomics features calculated based on PET/CT scans of DLBCL patients is accurate
Primary research question: What are the histopathological similarities and differences between ICI colitis, Crohn’s colitis, Ulcerative colitis and GvH-colitis?. Secondary research question: Does the presence and distribution of CD4+ T cells, CD8+ T…
Through their effect on blood pressure, concurrent use of ACEi or ARB in the perioperative period may contribute to hypotension and compromised tissue perfusion, leading to poor wound healing, renal injury, myocardial infarction, stroke and death.
It is feasible to applicate CPAP in the acute phase of stroke in AIS patients
Joint distraction using the userfriendly KneeReviver is clinically effective in the treatment of severe knee osteoarthritis, based on an increase in WOMAC score and an increase in joint space width.
It is hypothesised that optimizing visualization of the muscle boundries wil improve quantitative muscle ultrasound, which should increase the correlation between the outcome of quantitative muscle ultrasound and magnetic resonance imaging.
The efficacy of low dose amitriptyline on insomnia is equivalent to first choice treatment CBT-I.
- The effectiveness of an ACT intervention focused on values and willingness to take action is more effective in reducing depressive symptoms two weeks after the intervention, compared to an an ACT intervention focused on acceptance and defusion and…
Survival of transfused erythrocytes will depent on donor and unit characteristics
Based on a pilot study from the Amsterdam University Medical Center, we hypothesize that the FET is possibly less accurate to detect EPI in patients with pancreatic cancer and after a pancreatoduodenectomy (PD).
It is hypothesized that the new cement compression device leads to better cement distribution and penetration compared to the current technique (finger packing). It is also hypothesized that there will be less cement leakage and that the duration of…
The main study parameter is the agreement between ribociclib plasma levels of blood collected by venipuncture or DBS.
We hypothesize that trimetazidine improves left ventricular diastolic dysfunction in HFpEF, by improving mitochondrial function and increasing myocardial energy content
The teams in the intervention condition (implementation program) have implemented CAT better than the teams in de control condition.